Sketchy: Plasmodium

Question 1

Cue:

stinky warlord with 4 buttons

Answer 1

mal odor = Plasmodium malariae

4 buttons = 4 day cyclical fever

Question 2

What is the fever pattern for Plasmodium malariae?

Answer 2

every 4th day (72 hours)

Question 3

Cue:

warlord carrying an oval shield with a liver-shaped spot and an axe trying to hypnotize someone with a pendulum colored in an every-other pattern

Answer 3

oval = Plasmodium ovale
axe = Plasmodium vivax
hypnozoites in liver (dormant forms)
every other = fever every 48 hours

Question 4

What is the fever pattern for Plasmodium vivax?

Answer 4

every other day (48 hours)

Question 5

What is the fever pattern for Plasmodium ovale?

Answer 5

every other day (48 hours)

Question 6

Cue:

irregularly torn shirt and a red banana-shaped headdress and gold belt and chest plate

Answer 6

Plasmodium falciparum
irregular tears = irregular fever
headdress = cerebral malaria (occluded BVs in brain)
banana = banana-shaped on peripheral blood smear
chest plate = occlude vessels in the lungs
gold belt = occlude vessels in the kidneys

Question 7

What is the fever pattern for Plasmodium falciparum?

Answer 7

irregular

Question 8

How is plasmodium diagnosed?

Answer 8

blood stain and Giemsa smear to see parasites in RBCs

Question 9

What Plasmodium species causes the most severe disease?

Answer 9

Plasmodium falciparum

Question 10

Many anti-malarial drugs end in -____.

Answer 10

-quine

Question 11

Cue:

Color queen wearing colorful stringed beads

Answer 11

chloroquine

Question 12

Cue:

Primal Queen wearing animal skins

Answer 12

primaquine

Question 13

You must check for _____ before giving primaquine, or you could cause severe anemia.

Answer 13

G6PD

Question 14

You must check for G6PD before giving ______, or you could cause severe anemia.

Answer 14

primaquine

Question 15

You must check for G6PD before giving primaquine, or you could cause ______.

Answer 15

severe anemia

Question 16

Cue:

Me-Fly-Queen wearing lots of feathers in a palanquine with luggage on top

Answer 16

Me Fly Queen = mefloquine
luggage = prophylaxis for travelers
palanquine = stronger

Question 17

______ can be taken prophylactically by travelers headed to areas with chloroquine-resistant malaria.

Answer 17

Mefloquine

Question 18

Cue:

Atova vampire queen inside a palanquine with an inguna and luggage on top

Answer 18

atova vampire queen = atovaquone
iguana = proguanil
luggage = prophylaxis for travelers

Question 19

What is the tx for Plasmodium falciparum?

Answer 19

arta- drugs: artemisins

atovaquone/proguanil

Question 20

Cue:

artist threatening with a sickle

Answer 20

artist = artemisins (tx for falciparum)

sickle cell = protective against Plasmodium falciparum malaria

Question 21

Cue:

artist facing away from the action covered in ivy

Answer 21

artesunate

ivy = IV admin

Question 22

Cue:

Dining queen in a palanquine covered in tin cans and ivy

Answer 22

dining queen = quinidine
tin cans = tinnitus, HA (cinchonism)
ivy = IV admin

Question 23

What is a SE of quinidine?

Answer 23

cinchonism (HA, tinnitus)

Question 24

Cue:

Cow with liver-shaped, bursting, and ring-shaped spots standing next to red mushrooms

Answer 24

liver = where sporozoites mature into trophozoites 
bursting = schizont release
ring-shaped = infected RBCs
mushrooms = spores

Question 25

Malaria is transmitted via the ______, which carries the sporozoites in its saliva.

Answer 25

Anopheles mosquito

Question 26

Malaria is transmitted via the Anopheles mosquito, which carries the ______ in its saliva.

Answer 26

sporozoites

Question 27

______ mature to trophozoites in the liver.

Answer 27

Sporozoites

Question 28

Sporozoites mature to _____ in the liver.

Answer 28

trophozoites

Question 29

Sporozoites mature to trophozoites in the _____.

Answer 29

liver

Question 30

_____ divide into merozoites which burst from hepatocytes and infect RBCs.

Answer 30

Schizonts

Question 31

Schizonts divide into _____ which burst from hepatocytes and infect RBCs.

Answer 31

merozoites

Question 32

Schizonts divide into merozoites which burst from hepatocytes and infect _____.

Answer 32

RBCs