Sketchy: Plasmodium Flashcards
Cue:
stinky warlord with 4 buttons
mal odor = Plasmodium malariae
4 buttons = 4 day cyclical fever
What is the fever pattern for Plasmodium malariae?
every 4th day (72 hours)
Cue:
warlord carrying an oval shield with a liver-shaped spot and an axe trying to hypnotize someone with a pendulum colored in an every-other pattern
oval = Plasmodium ovale
axe = Plasmodium vivax
hypnozoites in liver (dormant forms)
every other = fever every 48 hours
What is the fever pattern for Plasmodium vivax?
every other day (48 hours)
What is the fever pattern for Plasmodium ovale?
every other day (48 hours)
Cue:
irregularly torn shirt and a red banana-shaped headdress and gold belt and chest plate
Plasmodium falciparum
irregular tears = irregular fever
headdress = cerebral malaria (occluded BVs in brain)
banana = banana-shaped on peripheral blood smear
chest plate = occlude vessels in the lungs
gold belt = occlude vessels in the kidneys
What is the fever pattern for Plasmodium falciparum?
irregular
How is plasmodium diagnosed?
blood stain and Giemsa smear to see parasites in RBCs
What Plasmodium species causes the most severe disease?
Plasmodium falciparum
Many anti-malarial drugs end in -____.
-quine
Cue:
Color queen wearing colorful stringed beads
chloroquine
Cue:
Primal Queen wearing animal skins
primaquine
You must check for _____ before giving primaquine, or you could cause severe anemia.
G6PD
You must check for G6PD before giving ______, or you could cause severe anemia.
primaquine
You must check for G6PD before giving primaquine, or you could cause ______.
severe anemia
Cue:
Me-Fly-Queen wearing lots of feathers in a palanquine with luggage on top
Me Fly Queen = mefloquine
luggage = prophylaxis for travelers
palanquine = stronger
______ can be taken prophylactically by travelers headed to areas with chloroquine-resistant malaria.
Mefloquine
Cue:
Atova vampire queen inside a palanquine with an inguna and luggage on top
atova vampire queen = atovaquone
iguana = proguanil
luggage = prophylaxis for travelers
What is the tx for Plasmodium falciparum?
arta- drugs: artemisins
atovaquone/proguanil
Cue:
artist threatening with a sickle
artist = artemisins (tx for falciparum)
sickle cell = protective against Plasmodium falciparum malaria
Cue:
artist facing away from the action covered in ivy
artesunate
ivy = IV admin
Cue:
Dining queen in a palanquine covered in tin cans and ivy
dining queen = quinidine
tin cans = tinnitus, HA (cinchonism)
ivy = IV admin
What is a SE of quinidine?
cinchonism (HA, tinnitus)
Cue:
Cow with liver-shaped, bursting, and ring-shaped spots standing next to red mushrooms
liver = where sporozoites mature into trophozoites bursting = schizont release ring-shaped = infected RBCs mushrooms = spores
Malaria is transmitted via the ______, which carries the sporozoites in its saliva.
Anopheles mosquito
Malaria is transmitted via the Anopheles mosquito, which carries the ______ in its saliva.
sporozoites
______ mature to trophozoites in the liver.
Sporozoites
Sporozoites mature to _____ in the liver.
trophozoites
Sporozoites mature to trophozoites in the _____.
liver
_____ divide into merozoites which burst from hepatocytes and infect RBCs.
Schizonts
Schizonts divide into _____ which burst from hepatocytes and infect RBCs.
merozoites
Schizonts divide into merozoites which burst from hepatocytes and infect _____.
RBCs
