Sexually transmitted disease Flashcards

1
Q

What is the most common cause of STI?

A

Chlamydia trachomatis

It is the most common cause of curable bacterial sexually transmitted infection (STI) worldwide. It manifests primarily as urethritis in males and endocervicitis in females

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2
Q

What is LGV?

A

LGV (lymphogranuloma venereum) LGV stands for lymphogranuloma venereum. It’s a type of chlamydia bacteria that attacks the lymph nodes, which are an important part of your body’s defence against infections. LGV is very rarely seen in heterosexual men and women in the UK but cases are being seen among gay and bisexual men.

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3
Q

What are the main STIs to learn about and their treatments?

A
  1. Chlamydia trachomatis (most common) - doxocycline
  2. Gonnorhea - ceftriaxone
  3. MGEN –> mycoplasma genitalium (like chlamydia) - doxocycline
  4. syphillis - penicllin benzathine
  5. genital ulcer disease - syphillis and herpes

6 HPV - ablation

7 Molluscum contagiosum - wait and see

  1. Herpes - HSV1 and HSV2 - aciclovir
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4
Q

Suggest the two main causes of genital ulcers

A

Syphillis (deeper)/ primary

Herpes

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5
Q

Suggest three causes of vaginal discharge

A

Thrust

Trichomonas vaginalis

Bacterial vaginosis

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6
Q

How do you treat trichomonas vaginalis?

A

Trichomoniasis can be cured with a single dose of prescription antibiotic medication (either metronidazole or tinidazole), pills which can be taken by mouth.

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7
Q

What STIs can be detected using microscope?

A

Syphillis and gonnorhea

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8
Q

How is each STI screened?

A
  1. Chlamydia trachomatis (most common) - NAAT
  2. Gonnorhea - cultures, NAAT and sensitivity
  3. MGEN –> NAAT
  4. syphillis - PCOT - point of care test, EIA IgG, RPR (rapid plasma reagin), VDRL (venereal disease research lab test)
  5. genital ulcer disease -

6 HPV -

7 Molluscum contagiosum -

  1. Herpes - HSV1 and HSV2 - NAAT
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9
Q

What is the prevalence of HIV in the UK?

A

103 800 people

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10
Q

Suggest two places HIV testing is done?

A

GUM clinic and antenatal screening

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11
Q

What is AIDS?

A

AIDS related illness

<200 CD4+ cells

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12
Q

What further testing must be done for AIDS patients?

A

TB, pneumonia and cancer

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13
Q

What is reactive arthritis?

A

Reactive arthritis, also called Reiter’s syndrome is a condition that causes redness and swelling (inflammation) in various joints in the body, especially the knees, feet, toes, hips and ankles.

It usually develops after you’ve had an infection, particularly a sexually transmitted infection or food poisoning.

In most cases, it clears up within a few months and causes no long-term problems.

Men and women of any age can get it, but it’s more common in men, and people aged between 20 and 40.

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14
Q

What are three main symptoms of reactive arthritis?

A

Conjuctivitis

Urethritis

Synovitis

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15
Q

What is SARA?

A

Sexually acquired reactive arthritis ( SARA) is a reactive arthritis caused by an immune reaction to an infection, often a sexually transmitted infection. It is caused by immune complexes ( so antibodies that fight infection and proteins from the infection) being deposited in the joints .

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16
Q

What are the symptoms of chlamydia?

A
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17
Q

What are the symptoms of gonnorhea?

A

Pain in sex for women (dys-par-reun-iaa) dyspareunia.

Bloody discharge for women.

Kidney problems

Reiter’s syndrome

Risk of PID and ectopic pregnancy

18
Q

What is the term for painful sex?

A

Dyspareunia

19
Q

What is the term for painful urination?

20
Q

What are some treatments for MGEN?

21
Q

What rash could this be from?

A

Syphillis

(so easy to treat)

22
Q

What type of infection is this?

A

Herpes labialis is HSV1

23
Q

What is this?

A

Disseminated HSV2

24
Q

What disease is this picture showing?

A

Molluscum contagiosum

25
What is this showing?
Strawberry cervix in trichomonas vaginalis
26
What is chlamydia charcterised by?Add
For the female a colourless discharge, dyspareunia, dysuria, usually assymptomatic but can increase risk of ectopic pregnancy. For men it mostly is mild, and causes dysuria and slight colourless discharge.
27
What are the complications of chlamydia?
SARA - sexually acquired reactive arthritis - HLA-B27 PID Ectopic pregnancy Epidydymoorchitis Infertility
28
How is chlamydia treated?
Doxocyline
29
30
What other condition is associated with chlamydia serovars?
Lymphogranuloma venereum Also treated doxocycline Characterised by haemmorhagic prostitis More common in MSM
31
What is perihepatitis otherwise known as? What is it?
Fitz-Hugh-Curtis syndrome. Fitz-Hugh-Curtis syndrome (FHCS) refers to the development of a perihepatitis in association with pelvic inflammatory disease (PID). Affects diapphrgamtic surface of liver. Mimics cholecystitis.
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How is gonnorhea treated?
Ceftriaxone 1g (increase in dose) intramuscularly as a single dose
34
What are two tests for syphillis?
Treponema and non-treponemal testing
35
What is TPPA?
Treponema pallidum particle agglutination assay Treponemal test
36
What is EIA?
Enzyme immunoassay
37
What is VDRL?
Non-treponemal testing Venereal Disease Research Laboratory test - anticardiolipin
38
What is RPR?
A rapid plasma reagin (RPR) test is a blood test used to screen you for syphilis. It works by detecting the nonspecific antibodies that your body produces while fighting the infection. Non specific
39
What are four tests for syphillis?
Microscopy EIA (enzyme immunosassay) + treponemal pallidum particle agglutination (TPPA) assay - specific RPR (rapid plasma reagin testing) + VDRL testing (venereal disease research lab test) - non specific
40
What is a symptom of trichomonas vaginalis?
Itching down below
41
When is sTRawberry cervix seen?
Trichomonas vaginalis
42