Clinical chemistry Flashcards

1
Q

What 4 ECG changes are seen with hyperkalemia?

A

Tall tented T waves

Large QRS

No P waves

Sine waves

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2
Q

What ECG changes are seen with hypokalemia?

A
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3
Q

What are some differences between azotemia and renal AKI?

A

Pre-renal has low urine sodium vs renal <15 vs >40

Prerenal has urea >>creatinine

Better fluid response

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4
Q

Causes of renal AKI?

A

iSCHAEMIA

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5
Q

When does a GP manage CKD?

A

STAGE 1 - 3A

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6
Q

How does a specialist measure CKD?

Treat CKD?

A

ACR and eGFR

Stage 3b-5

IV

Less K+ DIET
Erythropoietin
Alfacaldol
Phospjhate binders

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7
Q

What is the main cause of hypernatremia?

A

Low fluid or fluid depletion

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8
Q

How is sodium conc calculated?

A

ECF Na+/ ECF water

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9
Q

What should always be asked of eldrely?

A

Are they drinking water? (dementia)

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10
Q

What are two causes of hyponatremia?

A
  1. Reduced sodium due to excess of water
  2. Reduced sodium
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11
Q

What is the most common cause of hyponatremia?

A

Bendroflumethiaze diuretics

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12
Q

What is the difference between SIADH and excessive drinking?

A
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13
Q

What causes hyponatremia?

A

Increase intake of fluid

or reduced sodium

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14
Q

What causes hypernatremia?

A

Low water intake

(elderly hyper)

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15
Q

What calcium drives mechanisms?

A

Free calcium

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16
Q

What can affect calcium?

A

Albumin conc –> more albumin reduces free calcium

ph

Low ph –> more calcium (acidity

17
Q

What causes hypocalcemia?

A

Hypoparathyroidism

Acute pancreatitis

Magnesium (co-factor)

(EDTA)

18
Q

What hydroxylation happens in kidneys

A

1 hydroxylation

19
Q

What is pseudohypoparathyroidism?

A