Sepsis

Question 1

what is it

Answer 1

life threatening organ dysfunction caused by dysregulated host response to infection

Question 2

what is septic shock

Answer 2

subset of sepsis with circulatory and cellular / metabolic dysfunction associated with higher risk of mortality

Question 3

what is symptoms

Answer 3

patient looks ill
triggering early warning score (NEWS)
signs of infection

Question 4

what is cause

Answer 4

list is extensive

mostly gram negative bacilli

Question 5

how is it diagnosed

Answer 5

history
examination
investigations

Question 6

what things would be investigated

Answer 6

mircrobio - blood, stool, urine, wound, tissue culture 
microscopy - stool, urine, CSF, sputum 
serology 
antigen detection 
PCR/molecular studies

Question 7

treatment for sepsis and enterococci in GI tract

Answer 7

amoxicillin
cotrimoxazole is allergic and when criteria for oral switch
vancomycin also active

Question 8

treatment for sepsis and coliforms

Answer 8

gentamicin
azetreonam if allergic
co-trimoxazole when criteria for oral switch

Question 9

treatment for sepsis and anaerobes

Answer 9

metrondiazole IV then oral