Hepatitis B Flashcards
how is it transmitted
DNA virus transmitted via blood-blood, sexual intercourse or vertical transmission
what is incubation peroid
long, average 4 months
what is common cause
yellow fever virus
what is symptoms
similar to hep A but usually more severe - eg may have rash
how is it diagnosed
they antibody n antigen marker shitey things
what is hepatitis B surface antigen (HBsAg)
protein on surface of hep B virus
indicates person is infectious
what is hepatitis B surface antibody (anti -HBs)
indicates recovery and immunity from hep B virus
also develops if vaccinated
what is total hepatitis B core antibody (anti-HBc)
appears at onset of symptoms in acute hep B and persists for life
indicates previous or ongoing infection
what is IgM antibody to hep B core antigen (IgM anti-HBc)
indicates recent infection with hep B
presence indicates acute infection
what is treatment
alcohol avoidance
antivirals in chronic infection
IFNa sometimes used
what antivirals given
adefovir
tenofovir
entecavir
peginterferon
how is it prevented
safe blood safe sex needle exchange screening of pregnant women vaccine available for at risk individuals
what is the outcome
chronic hep D cirrhosis fulminant acute infection (fatal) hepatocellular carcinoma
