Autoimmune Hepatitis Flashcards
1
Q
what is it
A
chronic condition more frequent in young women
2
Q
what is classic case
A
young woman on pill
3
Q
what does it look like pathologically
A
periportal piecemeal necrosis
fibrosis
lobar involvement
4
Q
what causes it
A
viruses
toxins
drugs
5
Q
what are symptoms
A
hepatomegaly jaundice weight/appetite loss tired RUQ discomfort stigmata of chronic liver disease splenomegaly myalgia
6
Q
how is it diagnosed
A
increased AST increased ALT ANA +ve ASMA +ve Anti-LKM +ve Increased IgG
7
Q
how is it treated
A
azathioprine (immunosuppression)
prednisolone
ursodeoxycholic acid (bile acid)
liver transplant
