Hepatitis C Flashcards
1
Q
how is it transmitted
A
RNA virus transmitted via blood-blood and sexual intercourse
2
Q
does it develop chronic liver disease
A
yes
3
Q
is it most common in UK
A
yes
4
Q
what is incubation period
A
short (2 weeks - 6 months)
5
Q
what is common cause
A
herpes simplex virus
6
Q
what are symptoms
A
mild/absent
10% have mild flu like illness with jaundice and raised AST, ALT
may have pronounced fatigue
7
Q
how is it diagnosed
A
Hep C Ab + DNA
8
Q
how is it treated
A
IFNa
antivirals
9
Q
what antivirals used
A
peginterferon, ribavirin
10
Q
what is side effect of PEG
A
flu like symptoms, thyroid and autoimmune disease
11
Q
what is side effect of ribavirin
A
anaemia
12
Q
what is outcome
A
chronic infection (75%)
cirrhosis
resolution
