Non-Alcoholic Fatty Liver Disease (NAFLD) Flashcards
1
Q
what is it
A
deposition of fat in liver not attributable to alcohol intake
2
Q
what is chain of events leading up
A
steatosis (fat deposition) -> oxidative stress -> non-alcoholic steatohepatitis (NASH - type of nafld) -> fibrosis -> cirrhosis
3
Q
what causes it
A
obesity
type 2 diabetes
hypertension
hyperlipidaemia
4
Q
what are symptoms
A
most asymptomatic
signs of liver disease in later stage
5
Q
how is it diagnosed
A
US shows fatty liver
liver biopsy often diagnostic
6
Q
how is it treated
A
lifestyle advice
liver transplant at end-stage cirrhosis
