Primary Sclerosing Cholangitis Flashcards
1
Q
what is it
A
progressive fibrosis and obliteration of biliary tracts
2
Q
who is most commonly affected and what is it associated with
A
mostly men affected
associated with UC
3
Q
what are symptoms
A
asymptomatic fatigue fever RUQ pain pruritis weight loss
4
Q
how is it diagnosed
A
cholestatic LFTs (obstructive) pANCA +ve, ANA +ve
5
Q
what is treatment
A
prednisolone
methotrexate
