Sedative Drugs Flashcards

1
Q

barbiturates with long duration of action?

A

phenobarbital and mephobarbital

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

barbiturate with ultra short duration of action and used as anesthesia?

A

thiopental

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

barbiturates induce which enzymes?

A

cytochrome p450 enzymes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

barbiturates bind to which receptors?

A

GABA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

barbiturates increase … of Cl ion channel and hyperpolarization of neurons?

A

duration of opening

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

barbiturates exacerbate … ?

A

porphyria

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

benzodiazepines utilize the same receptors as …. ?

A

ethanol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

full benzodiazepine agonist; conscious sedation; pre-medication for dental or minor surgery?

A

midazolam

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

structurally not related to BZD; partial agonist of 5-HT receptors; affinity for D2 receptors?

A

buspirone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

what can block the effect of buspirone?

A

flumazenil

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

a competitive antagonist at BZD binding site on the GABA receptor; short acting?

A

flumazenil

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

short acting BZD used for sleep disorders?

A

triazolam

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

intermediate acting BZD hypnotics?

A

temazepam and estazolam

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

long acting BZD hypnotic?

A

flurazepam

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

non BZD hypnotics for sleep disorders?

A

zolpidem, zaleplon, eszopiclone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly