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Dental Pharmacology > Asthma and COPD > Flashcards

Asthma and COPD Flashcards

1
Q

antiinflammatory drugs: inhaled steroids

A

budesonide; beclomethasone; fluticasone; mometasone; (ciclesonide)

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2
Q

antiinflammatory drug: modulator of mast cell degranulation; mast cell stabilizer

A

cromolyn

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3
Q

antiinflammatory drug: modulator of mast cell degranulation; anti-IgE

A

omalizumab

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4
Q

leukotriene modifiers: leukotriene receptor antagonists

A

montelukast; (zafirlukast)

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5
Q

leukotriene modifier: 5-LO (lipoxygenase) inhibitor

A

zileuton

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6
Q

bronchodilators: short acting B2 agonists

A

albuterol; (levalbuterol); (pirbuterol)

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7
Q

bronchodilators: long acting B2 agonists

A

salmeterol; formoterol; indacaterol

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8
Q

bronchodilators: methylxanthines

A

theophylline; aminophylline

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9
Q

bronchodilators: muscarinic receptor antagonists

A

ipratropium; tiotropium

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10
Q

bronchodilator: PDE-4 inhibitor

A

roflumilast

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11
Q

which bronchodilator should always be in your dental emergency kit?

A

albuterol

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12
Q

Which receptors?: located in large bronchioles; vagal innervation

A

cholinergic (M2) receptors

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13
Q

which receptors?: located in small bronchioles; no direct innervation

A

B2 receptors

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14
Q

anticholinergic: inhaler: response varies: increased broncho-selectivity by poor mucosal and CNS uptake

A

ipratropium bromide

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15
Q

anticholinergic: long duration of action: approved for COPD

A

tiotropium bromide

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16
Q

2 x daily dosing long acting B2 agonists

A

salmeterol; formoterol

17
Q

1 x daily dosing long acting B2 agonist

A

indacaterol

18
Q

theophylline and diethylamine

A

aminophylline

19
Q

useful for allergic asthma; non-specific stabilizer of mast cell; inhibit cough by their action on airway nerves

A

cromolyn sodium

20
Q

oral corticosteriods

A

methylprednisolone, prednisolone

21
Q

“soft steroid”

A

ciclesonide

22
Q

the most effective agents for acute attacks unresponsive to bronchodilators; restores B receptor therapy

A

oral or parenteral glucocorticoids

23
Q

systemic effects of what?: decreased bone density in premenopausal women and decreased rate of growth in children

A

inhaled glucocorticoids

24
Q

CYP2CP and 3A4 inhibited by …

A

zafirlukast

25
Q

receptor blockers?

A

“kasts”

26
Q

synthesis blockers; inhibits leukotriene formation

A

zileuton

27
Q

prophylaxis of moderate to severe aeroallergen associated asthma; prevents binding of IgE to a variety of cells (mast cells) associated with allergic response; SC injection

A

omalizumab

28
Q

PDE4 inhibitor

A

roflumilast

Dental Pharmacology (30 decks)

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