Angina Flashcards
only class to get vasodilation and venodilation
nitrates
venodilation results in decreased …
preload
effect of nitrates on BP
unchanged or slight decrease
effect of nitrates on HR
unchanged or slight decrease
Do not take … with nitrates because it increases cGMP by preventing metabolism, potential for augmented cGMP response to nitrates, profound hypotension, myocardial ischemia
sildenifil (viagra)
non-dihydropyridine CCBs
verapamil, diltiazem
dihydropyridine CCBs
nifedipine, felodipine
use-dependent binding (targets cardiac cells)
non-DHPs
voltage-dependent binding (targets vascular smooth muscle)
DHPs
which group?: blunts heart rate and inotropic response to exercise; reduces afterload; does not reduce preload; does not prevent coronary vasospasm
B blockers
abrupt … of B blocker may induce rebound tachycardia: unstable angina or MI
withdrawal
B blockers are ineffective in the treatment of …
vasospastic (prinzmetal’s) angina
novel metabolic modulator; MoA is unknown; has ZERO hemodynamic effects; will not relieve acute angina attacks
Ranolazine
gingival inflammation
Ca channel blockers
