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Dental Pharmacology > IV Anesthetics > Flashcards

IV Anesthetics Flashcards

1
Q

induction agents?

A

thiopental, etomidate, propofol, methohexital

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2
Q

Which tends to produce depressing effects in specific areas?

A

ketamine

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3
Q

which tends to produce global depressing effects?

A

thiopental

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4
Q

affect GABA system?

A

barbiturates, benzodiazepines, etomidate

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5
Q

affects glutamate system?

A

ketamine

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6
Q

bifunctional activity: GABA and glutamate?

A

propofol

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7
Q

which class prolongs binding of GABA to receptor?

A

barbiturates

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8
Q

which class causes an allosteric change in GABA receptor activity?

A

benzodiazepines

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9
Q

which drug is the exception and increases CBF, ICP, MAP, CO?

A

ketamine

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10
Q

which drug neither stimulates nor inhibits the cardiovascular system?

A

etomidate

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11
Q

a barbiturate so increased cytrochrome P450 activity (increase metabolic activity; enzyme induction); porphyria?

A

thiopental

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12
Q

anitemitic qualities (induce vomiting)?

A

propofol

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13
Q

inhibition of steroidogenesis; not used in ICU?

A

etomidate

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14
Q

analgesic; IM route; intact pharyngeal and laryngeal reflexes; bronchodilator for refractory asthma; hallucinations (may require w/ benzodiazepine)?

A

ketamine

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15
Q

dissociative agent: eyes open but unconscious and pain free?

A

ketamine

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16
Q

which class of drug: anticonvulsant; amnesia; wide safety margin; minimal CV and respiratory depression; useful where no analgesia required?

A

benzodiazepines

17
Q

specific antagonist of benzodiazepines?

A

flumazenil

18
Q

3 benzodiazipines?

A

diazepam; lorazepam; midazolam

19
Q

half life of diazepam?

A

20-40

20
Q

half life of lorazepam?

A

10-20

21
Q

half life of midazolam?

A

2-4

22
Q

opioid antagonists?

A

naloxone; nalmefene

23
Q

opioid overdose triad?

A

pinpoint pupils; decreased respiration; coma

24
Q

a new opioid class w/ potent analgesic activity, rapid onset, short half life; non cumulative effects; rapid recovery?

A

remifentanil

25
Q

long lasting opioid?

A

morphine

26
Q

opioid: more lipid soluble; peak effect in 2-3 min; nausea and vomiting rare?

A

fentanyl

27
Q

in malignant hyperthermia, which receptor is affected by the drug to cause dramatic release of calcium

A

ryanodine receptor

28
Q

antidote to malignant hyperthermia?

A

dantrium

Dental Pharmacology (30 decks)

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