SDR MA Flashcards
Testicular capsule consists of
Visceral tunica vaginalis (mesothelial) Tunica albuginea (collagen) Tunica vasculosa (support for vasculature)
Human Legdig cells contain what structures?
crystals of Reinke
How many lobules are in the testes?
How many tubules in each lobule?
250
1-4
tubules
join at both ends with the rete testis
surrounded by tunica propria boundary tissue
basement membrane of basal lamina and lamina reticularis
seminiferous epithelium composed of germ cells and Sertoli cells
complex stratified epithelium
transitional zone/terminal segment of only Sertoli
spermatogenesis
speratozoa from diploid spermatogonia to haploid spermatozoa
2n -> 2n -> 4n -> meiotic phrophase with chromatin rearrangment -> 2n -> 1n
Sertoli cells
base of seminiferous tubules to its lumen
dipoid and non-dividing
lobulated nucleus and indented nuclear membrane
sustentacular (supportive)
Tight junctions between them
regulates product transport at blood testis barrier
stages of chromatin rearrangement in meiotic prophase of spermatocytes
leptotene zygotene pachytene diplotein
Spermoienesis
spermatids -> spermatozoa
Sertoli cell only syndrom
cause of infertility
caused by aspermatogenesis - absense of germ cells
Also happens with Irradiation
What happens due to incomplete cytokinesis
germ cells of the same generation are connected by cytoplasmic brudges and develop synchronously
Orchitis
inflammation of the testis - mumps
raise pressure in testis leading to atrophy of the seminiferous tubules and eventually sterility
Testicular cancers
almost always malignant
chemo works in 90% of cases
Intratesticular exurrent ducts
tubulus rectus
rete testis
first part of the ductuli efferents
tubulus rectus
cuboidal epithelium
covered by very short microvilli and some flagellum
Rete testis
in the mediastinum
cuboidal epithelium
short microvilli some flagellum
dense connective tissue for vasculature
Ductuli Efferentes
10-20 extra-testicular
lined by simple columnar
with principal cells with microvilli
and cilicated cells with celia
Principal cells of the ductuli efferent
reabsorb fluid
concentration of sperm
highly vascularized to help reabsorption
Ciliated cells
move sperm thru the ducts
3 mechanisms of moving sperm thru ductuli efferentes
hydrostatic pressure from testis
beating of cilia
peristaltic contraction of periductal smooth muscle cells
ductuli efferents are derived from
embryological mesonephric tubules (hence fluid reabsorption)
Cauda epididymis
periductal muscle layer
stores sperm
ductus epididymidis derives from
mesoneprhic duct