Review+Histo Flashcards

1
Q

capillary loops supplying tubules of juxta medullary nephons

A

vasa recta

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1
Q

have one primary ciluhm and ADH sensitive AQP-2 channels

A

principal cells

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2
Q

capillary bed of the tubules of cortical nephrons

A

tubular plexus

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2
Q

entirity of nehpron =

A

uriniferous tubule

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2
Q

tissue type

outer parietal layer =

visceral layer =

urinary space between =

A

parietal = simple squamos

visceral - simple epithelium, podocytes

space = space

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2
Q

morphology of renin producing cells of JG apparatus

A

specialized smc in wall of efferent arteriole

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3
Q

components of filtration membrane

A

glomerular capillary endothelium

basement membrane

podocyte foot processes

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4
Q

primary barrier to proteins

A

basement mebrane

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5
Q

thick portions of loop of henle lined with,

thin segments with

A

thick with cuboidal epithelium

thin with simple squamous

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6
Q

tip of renal pyramind

A

papilla

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7
Q

___ is permeable to water, while ___ is not, allowing the set up of an ion gradient

A

thin discending permeable

thin ascending not

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8
Q

tissue type straight portion of proximal tubule (thick descending limb)

A

cuboidal epithelium

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9
Q

ADH dependent segment,

epithelium contains principal cells

transition between nephron and collecting duct

A

collecting tubules (late distal)

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10
Q

tissue level, kidneys

A

retroperitoneal

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11
Q

2 capilary systems of kidney

A

glomerulus

tubular plexus/vasarecta

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12
Q

spinal levels kidneys sympathetic imput

levels for bladder and ureter

A

T12-L3

T11-L2

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13
Q

tissue type Proximal tubule covuluted portion

A

cuboidal/columnar cells with granular cytoplasm and basal nuclei

apical brush border with glycocalyx obscures lumen

14
Q

tissue type straight distal tubule (thick ascending)

A

cuboidal epithelium)

scant microvili, tight junctions

16
Q

% of cardiac output to kindeys

A

20-25%

17
Q

foot processes of podocytes of visceral layer of bomans capsule

A

pedicles

18
Q

pericyte smooth muscle cells contain receptors for

A

ANP and angiotensin II

19
Q

morphology of extraglomerular mesangial (lactis) cells of JG apparatus

A

connected to renin producing cells (JG cells) via gap junctions

20
Q

action of EPO,

produced by

A

increase mitosis of RBC precursors

increase RBC from marrow

produced by cortical interstitial cells

22
Q

loop of henle morphology cortical nephrons

A

external to juxtamedullary zone, short loops with only descending thin limb

23
Q

components of renal intersittium

A

interstitial conenctive tissue

interstitial fibroblast in cortex and medulla

24
Q

morphology juxtamedullary neprhons

A

long looped with ascending and descending thin limbs

25
Q

action collecting tubules (late distal) and action collecting ducts

A

principle cells - aquaporins permeable to water

intercalated cells - regulate acid/base of blood and body tissue, H transport, Bicarb production

26
Q

fibrous tissue surrounding kidney

A

capsule

27
Q

tissue type collecting tubules (late distal tubule) and collecting ducts

A

cuboidal cells (principal, light)

intercalated cells (dark)

distinct cell borders

28
Q

role of concurrent multiplier

countercurrent exchanger

A

urine concentration

protect ion gradient

29
Q

morphology of macula densa of JG apparatus

A

columnar cells of distal convuluted tubules

30
Q

mucosa of calyces, pelvis and ureters morphology

A

transition epithelial

lamina propia contains abundant elastic tissue

31
Q

tissue type distal tubule convoluted (early distal tubule)

A

cuboidal epithelium

scant microvili with fewer basal interdigitatiosn

32
Q

action convuluted distal tubule (early distal tubule)

A

Na responsive

CL K and HC03 reabsorbedd

K urate, H, N3H secreted

33
Q

proteins mediating nonmotile primary cilium acting as flow sensor in colelcting duct principal cells

defects in these cause __

A

polycystin 1+2

(defects cause polycystic kidney disease)

35
Q

action at straight distal tubule (thick ascending)

A

imperable to water,

Na, Cl and water reabsorbed

glucose, amino acids, prtoeins absorbed via facilitated transport

H ions secreted

36
Q

4 parts of loop of henle

A

straight proximal (thick descending)

thin descending

thin ascending

straight distal tubule (thick ascending)

37
Q

segments of male urethra

tissue type (male and female)

A

prostatic, membranous, penile

transitional psuedostratified squamous epithelium

38
Q

action of macula densa of JG apparatus

A

detects N and Cl concentration for renin producing (JG) cells resulting in alterations of the filtration rate and blood volume autoregulation

39
Q

referred pain level from kidney

A

T10-L2

40
Q

in convuluted portion of proximal tubules, lateral interdigitations between epitelial cells make ____ indistinguishable

A

lateral cell membranes