Review+Histo Flashcards
capillary loops supplying tubules of juxta medullary nephons
vasa recta
have one primary ciluhm and ADH sensitive AQP-2 channels
principal cells
capillary bed of the tubules of cortical nephrons
tubular plexus
entirity of nehpron =
uriniferous tubule
tissue type
outer parietal layer =
visceral layer =
urinary space between =
parietal = simple squamos
visceral - simple epithelium, podocytes
space = space
morphology of renin producing cells of JG apparatus
specialized smc in wall of efferent arteriole
components of filtration membrane
glomerular capillary endothelium
basement membrane
podocyte foot processes
primary barrier to proteins
basement mebrane
thick portions of loop of henle lined with,
thin segments with
thick with cuboidal epithelium
thin with simple squamous
tip of renal pyramind
papilla
___ is permeable to water, while ___ is not, allowing the set up of an ion gradient
thin discending permeable
thin ascending not
tissue type straight portion of proximal tubule (thick descending limb)
cuboidal epithelium
ADH dependent segment,
epithelium contains principal cells
transition between nephron and collecting duct
collecting tubules (late distal)
tissue level, kidneys
retroperitoneal
2 capilary systems of kidney
glomerulus
tubular plexus/vasarecta
spinal levels kidneys sympathetic imput
levels for bladder and ureter
T12-L3
T11-L2
tissue type Proximal tubule covuluted portion
cuboidal/columnar cells with granular cytoplasm and basal nuclei
apical brush border with glycocalyx obscures lumen
tissue type straight distal tubule (thick ascending)
cuboidal epithelium)
scant microvili, tight junctions
% of cardiac output to kindeys
20-25%
foot processes of podocytes of visceral layer of bomans capsule
pedicles
pericyte smooth muscle cells contain receptors for
ANP and angiotensin II
morphology of extraglomerular mesangial (lactis) cells of JG apparatus
connected to renin producing cells (JG cells) via gap junctions
action of EPO,
produced by
increase mitosis of RBC precursors
increase RBC from marrow
produced by cortical interstitial cells
loop of henle morphology cortical nephrons
external to juxtamedullary zone, short loops with only descending thin limb
components of renal intersittium
interstitial conenctive tissue
interstitial fibroblast in cortex and medulla
morphology juxtamedullary neprhons
long looped with ascending and descending thin limbs
action collecting tubules (late distal) and action collecting ducts
principle cells - aquaporins permeable to water
intercalated cells - regulate acid/base of blood and body tissue, H transport, Bicarb production
fibrous tissue surrounding kidney
capsule
tissue type collecting tubules (late distal tubule) and collecting ducts
cuboidal cells (principal, light)
intercalated cells (dark)
distinct cell borders
role of concurrent multiplier
countercurrent exchanger
urine concentration
protect ion gradient
morphology of macula densa of JG apparatus
columnar cells of distal convuluted tubules
mucosa of calyces, pelvis and ureters morphology
transition epithelial
lamina propia contains abundant elastic tissue
tissue type distal tubule convoluted (early distal tubule)
cuboidal epithelium
scant microvili with fewer basal interdigitatiosn
action convuluted distal tubule (early distal tubule)
Na responsive
CL K and HC03 reabsorbedd
K urate, H, N3H secreted
proteins mediating nonmotile primary cilium acting as flow sensor in colelcting duct principal cells
defects in these cause __
polycystin 1+2
(defects cause polycystic kidney disease)
action at straight distal tubule (thick ascending)
imperable to water,
Na, Cl and water reabsorbed
glucose, amino acids, prtoeins absorbed via facilitated transport
H ions secreted
4 parts of loop of henle
straight proximal (thick descending)
thin descending
thin ascending
straight distal tubule (thick ascending)
segments of male urethra
tissue type (male and female)
prostatic, membranous, penile
transitional psuedostratified squamous epithelium
action of macula densa of JG apparatus
detects N and Cl concentration for renin producing (JG) cells resulting in alterations of the filtration rate and blood volume autoregulation
referred pain level from kidney
T10-L2
in convuluted portion of proximal tubules, lateral interdigitations between epitelial cells make ____ indistinguishable
lateral cell membranes
