Resp Viruses Flashcards
responsible for summer “cold and flu” resp infections and undifferentiated fevers
enteroviruses
___ complications of parainfluenza virus infections common in young,
may progess to ___
lower respiratory conplications
Croup
basic clinical features influenza
self-limited 3-7 days
secondary bacterial infections cause of death:
strep pneumo
staph a.
haemophilus influenzae
subacure scleorising panencephalits in measels infection
CNS - personality
behavior
memory changes
myclonic jerks
spasticity
blindness
(drugs)inhibit uncoating by blocking M2 proteins
amantadine
rimantidine
temperature sensitivity rhinovirus
grows better at 33 than 37
pharyngocojunctival fever in adenovirus infection
red eyes
sore throat
febrile
vaccine adenovirus
not for public (type 4 and 7 in works)
virus morphology picorna
+RNA non-enveloped
pathogenesis influenza
infects ciliated epithial cells
replication destroys resp epithelium
cytotoxic T cell - mediated damage
(viremia does NOT play a major role)
vaccine respiratory syncytial virus
natural infection does not prevent re-infection
re-infection especially risky in elderly
emerging resp viruses isolated to bats > pigs > humans in australia and Asia
hendra virus
nipah virus
dates and transmission H5N1
2003-Junly 2014
does not transmit easily among people
household poultry or contaminated environment
adenovirus disease sequale
acute resp disease
pneumonia
pharyngoconjunctival fever
conjunctivitis
GI
hemorrhagic cystitis (bladder inflam)
treatment for respiratory syncytial virus
healthy infant
premature/immunocompromised infant
premature infants
healthy - supportive O2, fluids, nebulized cold steam
**premature or immunocomp: **aerosolized ribavirin
**premature infants: **passive immunisation with anti-RSV Ig and humanized monoclonal abx
vaccines metapneumovirus
none (or therapies)
virus morphology orthomyxo and paramyxo viruses
-RNA,
enveloped
influenza A, B C, virus morphology and family
orthomyxoviridae
segmented -RNA
enveloped
atypical measels presentatoin
intense rash
vesicles, petechiae, prupura, or urticaria
vaccines Rhinovirus
none