Clinical Diffusion Capacity

Question 1

in normal. O2 is largely ___ limited

Answer 1

perfusion limited

Question 2

average DLco of resting adult in singel breath method

Answer 2

25ml of CO/min/mmHg

Question 3

impact of exercise on DLco

Answer 3

increased x2-3

Question 4

impact of muscular dystrophy

Answer 4

single breath DLco decreased

low vital capacity

Question 5

clinical significane of DLco/VA is high/low

Answer 5

low

Question 6

diffusion capacity in asthma

why?

Answer 6

increased

increased negative intrathoracic pressure

increased thoracic blood volume

Question 7

impact on DLco of any condition that increases lung blood flow

Answer 7

increased

Question 8

silicosis impacts surface area/distance

Answer 8

distance

Question 9

normal spirometry, decreased diffusion = (3)

Answer 9

Pul HTN

emphysema AND ILD (obstruction and constriction)

anemia

Question 10

hallmark lesion of pul htn

Answer 10

pelxiform lesion, thick, inflammed

Question 11

impact of valsalva manuever

Answer 11

decreased DLco due to decreased thoracic lung volume

Question 12

impact of pt not taking 100% breath during breath hold

Answer 12

low DLco