Acute kidney injury Flashcards
post renal AKI =
impaired effective renal perfusion
post renal aki =
obstruction of urinary flow
differentiate volume depletion vs ATN proximal tubular injury
FEna < 1% = volume depletion
FENa > 2% = ATN
rule out post-renal aki via
renal imaging
oliguria =
urine 400-500ml/day
in prerenal aki
decreased perfusion > ___ > increased reabsorption of Na at ____ > appropriate oliguria
decreased perfusion > increased AngII and ADH > increased abs of Na at proximal tubule **> **appropriate oliguria
azotemia =
elevated nitrogen waste products related to insufficient blood filtering
hydronehprosis in post-renal AKI
distention and dilation of renal pelvis calyces
nitrogenous waste product of protein metabolism, less reliable than creatinine due to variation in protein intake, catablolic rate and tubular reabsorption
BUN
AKI dianositc criteria
48 hours
increase in serum creatinine of 0.3mg/dl OR
50% increase in creatinine OR
reudction of urine <500ml in 24 hours
renal aki =
intrinsic renal disease (glomerular, tubular, interstitial, vascular)
uremia =
kidney failure > toxic effects of high nitrogenous substances in blood
FENa% =
Una (PCr)
______
PNa(UCr)
granular casts (muddy brown urine) seen in cases of
acute tubular necrosis
morphologic features ATN
tubular dilation
attenuation of tubular epithelium
loss of epithelial brush border
granular casts
mitotic figures (regenerative change)
