Clinical Hypoxemia

Question 1

50% hemoglobin saturation at

Answer 1

27mmHg of 02

Question 2

signs of hyper-capnic resp failure

Answer 2

sonulent

asterixis

Question 2

in chronic COPD, patients adapt to ___- by ____

Answer 2

adapt to increasing CO2 by retaining bicarb at the kidney

Question 3

peripheral censors

Answer 3

coratid body

aortic body

pumonary body

chest wall muscle

Question 3

ventilatory response to increase in PaC02 to 60mmHg

Answer 3

increase resp rate and tidal volume

Question 5

ventilatory response to PaO2 begins at

Answer 5

less than 70mmHg

Question 6

Haldane effect

Answer 6

admin of O2 satursates Hemoglobin

CO2 no longer buffered by hemoglobin > increased PaCO2 and chronic hypercapnia

Question 7

paradoxical abdominal breathing

Answer 7

sinking of abdomen in accessory breathing as diaphram fatigues

Question 9

central receptors

Answer 9

brainstem: ventrul medullary surface

tractus solitarius

locus ceruleus

Question 10

hypoxic vascoconstriction

Answer 10

alveolar damage

admin oxygen > blood flow increases in areas of of damage

increases V/Q mismatch and resulting hypercapnia

Question 11

when PCO2 rises….

Answer 11

alveolar ventilation increases

Question 12

what is collectively sensed by the chemoreceptors?

Answer 12

PaO2

PaCO2

[H]

Question 13

in chronic COPD, respiratory drive is

Answer 13

PaO2

(following habitation to increased CO2 by increasing bicarb)

Question 14

central receptors resposnsible for __% of response

peripheral for __%

Answer 14

70% central

30 peripheral

Question 15

normal [H] of blood

Answer 15

40 nano moles/L