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Pharmacology & Drugs > Respiratory Drugs- COPD and asthma > Flashcards

Respiratory Drugs- COPD and asthma Flashcards

1
Q

Mometasone

A

Inhaled corticosteroids

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2
Q

interactions with fluticasone

A

Strong inhibitor of 3A4

May increase chances of systemic corticosteroid effects

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3
Q

Albuterol

A

Short Acting Beta Agonist

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4
Q

Uses for triamcinolone

A

Prophylactic for asthma, can also be used to weene off systemic corticosteroids

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5
Q

Zafirlukast

A

Leukotriene inhibitor

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6
Q

Salmeterol

A

Long Acting Beta Agonist

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7
Q

Tiotropium

A

Anticholinergic

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8
Q

Use of budesonide

A

Maintenice of asthma in >6

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9
Q

MOA of Zafirlukast

A

Antagonist of D4 and E4, components of slow reacting anaphylaxis

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10
Q

What are the drug drug interactions of Zileuton

A

Increases theophylline levels, warfarin levels, propranolol levels and beta blocker activity

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11
Q

Uses for pirbuterol

A

Prevention and reversal of bronhcospasms in patients >12

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12
Q

Acilinium

A

Anticholinergic

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13
Q

When is terbutaline used

A

Prophylaxis for ages >12

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14
Q

Uses of olodaterol

A

Once daily for COPD

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15
Q

Uses for fluticasone

A

Prophylactic for younger than 4 years old

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16
Q

Uses for metaproterenolol

A

Bronchodilation for asthma or COPD

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17
Q

Use of Zafirlukast

A

Prophylaxis and chronic treatment of asthma in adults and children >5

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18
Q

Beclomethasone

A

Inhaled corticosteroids

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19
Q

What is the method of administration for terbutaline

A

IV

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20
Q

Metabolism of salmeterol

A

3A4

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21
Q

What is the adverse effect with beclomethasone

A

Care when transferring from systemic corticosteroids due to death from adrenal insufficiency. It takes time for the axis to recover

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22
Q

Ipratropium

A

Anticholinergic

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23
Q

Uses of indacaterol

A

COPD`

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24
Q

What are the adverse effects of Zafirlukast

A

Hepatotoxicity

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25
Q

Pirbuterol

A

Beta agonist

26
Q

MOA for Monelukast

A

Selectively binds to CysLT1 receptor, inhibiting D4 without any agonist activity.

27
Q

Olodaterol

A

Long Acting Beta Agonist

28
Q

Ciclesonide

A

Inhaled corticosteroids

29
Q

Adverse effects of Fomoterol

A

Asthma related deaths and hospitalizations if not already on a long term controller of asthma

30
Q

What is a risk for all long Acting Beta Agonist

A

Increased risk for asthma related deaths and hospitalizations

31
Q

Use for Monelukast

A

Allergies and prevention of asthma attacks

32
Q

Cautions of budesonide

A

Milk allergies or where primary treatment of status asthmaticus or acute episodes where intenstive measures are needed

33
Q

Fluticasone

A

Inhaled corticosteroid

34
Q

Use of salmeterol

A

Asthma in pts >4, exercise induced asthma, maintenence of COPD

35
Q

Adverse effects of metaproterenolol

A

CV negative effects

36
Q

Theophylline

A

Methylxanthines

37
Q

Fomoterol

A

Long Acting Beta Agonist

38
Q

Indacaterol

A

Long Acting Beta Agonist

39
Q

Uses for mometasone

A

Asthma prophylactic in patients >4

40
Q

Triamcinolone

A

Inhaled corticosteroid

41
Q

Metabolism of budesonide

A

CYP3A4

42
Q

Budesonide

A

Inhaled corticosteroids

43
Q

MOA of Zileuton

A

Inhibitor of 5-lipoxygenase, so all of B4,C4,D4,E4

44
Q

Use for levalbuterol

A

Prevention or treatment of bronhcospasms in pt >4

45
Q

Flunosolide

A

Inhaled corticosteroids

46
Q

Omalizumab

A

Monoclonal antibody to IgE

47
Q

Use for fomoterol

A

Treatment of asthma >5 yrs old, as an add on to long term corticosteroids, prevention of excersice induced asthma, treatment of COPD

48
Q

What is the drug interactionwith zafirlukast

A

Coadministration with Warfarin will increase the prothrombin time

49
Q

Montelukast

A

Leukotriene antagonist

50
Q

Uses for Omalizumab

A

Severe asthma in pts older than 6, chonic idiopathic urticaria

51
Q

3 methods of bronchodilation

A
  • B2 agonsts
  • Anticholinergic
  • Methlyxanthines
52
Q

Adverse effects of salmeterol

A

Severe allergies to milk

Patients must be on concurrent use of inhaled corticosteroid

53
Q

Terbutaline

A

Beta Agonist

54
Q

Levalbuterol

A

Beta agonist

55
Q

Zileuton

A

Leukotriene antagonist

56
Q

What conditions are contraindicated for theophylline

A

Active Peptic ulcer disease
seizure diseases
cardiac arrhythmias

57
Q

What are the adverse effects of tiotropium

A
  • Not for acute use or rescue medication

- Immediate hypersentitivity risk, especialy with milk protieins

58
Q

Use for ciclesonide

A

Prophalayxis for >12 yrs old

59
Q

Effects of methylxanthines

A

Broncho dilation

suppression of the airway responses

60
Q

Uses for flunosolide

A

Maintenance of asthma in >6 years old, and in those trying to weene off of oral corticosteroids

61
Q

Adverse effects of Zileuton

A

Pharynolaryngeal pain, elevation of hepatic enzymes

62
Q

Metaoroterenol

A

Beta agonist

Pharmacology & Drugs (43 decks)

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