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Pharmacology & Drugs > Neuro-Anesthetic Drugs > Flashcards

Neuro-Anesthetic Drugs Flashcards

1
Q

What is the common use for benzocaine

A

Local anesthetic:

-Poor water solubility, so a topical cream for derm, hemorrhoids, premature ejaculation, anesthetic lubricant

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2
Q

What is the common use for bupivacaine

A

Local anesthetic:

-long duration, usually for sensory block

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3
Q

What is the common use for cocaine

A

Local anesthetic:

-bloackage of nerve impulses, topical in upper respiratory

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4
Q

What is the common use for dibucaine

A

Local anesthetic:

-Toxic during injection, so topical cream only

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5
Q

What is the common use for lidocaine

A

Local anesthetic:

-faster, more intense, longer lasting, and antiarrythmic

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6
Q

What is the common use for procaine

A

Local anesthetic:

-Lower potently, longer onset, shorter duration, used only for infiltrate anesthesia

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7
Q

Which local anesthetic drug can not be given with sulfonamide antibiotics

A

Procaine

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8
Q

What is a major toxic side effect of halothane

A

Hepatitis (2 days to 3 weeks following exposure)

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9
Q

What is a major side effect of enflurane

A

Renal toxicity (due to fluorinated metabolites)

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10
Q

What is a major side effect of sevoflurane

A

Renal toxicity (due to fluoridated metabolites)

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11
Q

What is the antidote for malignant hyperthermia

A

Dantrolene

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12
Q

What are the properties of pharmokinetics of propofol

A

Metabolized in the liver very quickly, so fast onset and recovery

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13
Q

What are the system effects of propofol

A
  • Decrease in BP

- Respiratory depression

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14
Q

What are the systemic effects of fospropofol

A

Same a propofol, but prolonged onset and recovery

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15
Q

What are the method that etomidate is used for analgesia

A

Hypnotic, not analgesic

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16
Q

What are the systemic effects of etomidate

A
  • CV stability

- suppression of steroid production

17
Q

What are the characteristics seen in administration of ketamine

A
  • Catatonia, amnesia, and analgesia

- with or without loss of consciousness

18
Q

What are the systemic effects seen by ketamine

A
  • increased cerebral blood flow

- CV stimulator

19
Q

What class of drug is fentanyl

A

Opioid analgesic

20
Q

What class of drug is sufentanil

A

Opioid anesthetic

21
Q

What class of drug is remifentanil

A

Opioid analgesic

22
Q

What class of drug is morphine

A

Opioid anesthetic

23
Q

What class of drug is thopental

A

Barbiturate

24
Q

What class of drug is methohexital

A

Barbiturates

25
Q

What are the induction/recovery times, along with the the characteristics of Etomidate

A

Rapid onset, moderate recovery

-Provides CV stability, decreased steroidogensis and muscle movements

26
Q

What are the induction/recovery times, along with the the characteristics of ketamine

A

Moderate rapid onset/recovery

-CV stimulation and increased cerebral flow

27
Q

What are the induction/recovery times, along with the the characteristics of methohexital

A

Rapid onset and recovery

-Used for short ambulatory procedures

28
Q

What are the induction/recovery times, along with the the characteristics of midazolam

A

Slow onset and recovery

-balanced anesthetic, CV stability and amnesia

29
Q

What are the induction/recovery times, along with the the characteristics of propofol

A

Rapid onset and recovery

-antimemetic

30
Q

What are the induction/recovery times, along with the the characteristics of thiopental

A

Rapid onset and recovery (bolus dependent with slow recovery following IV)
-CV depression

31
Q

Which population should thiopental be avoided in

A

Porphyria patients

32
Q

What are the induction/recovery times, along with the the characteristics of fentanyl

A

Slow onset and recovery

-analgesic

33
Q

What is the drug to reverse midazolam

A

Flumazenil

34
Q

What is the drug to reverse fentanyl

A

Naloxone

Pharmacology & Drugs (43 decks)

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