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Pharmacology & Drugs > GI- IBD Drugs > Flashcards

GI- IBD Drugs Flashcards

1
Q

What drug class is Olsalazine

A

5-ASA

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2
Q

What are the classes of drugs that can be given for UC

A

-5-ASA
JAK inhibator
TNF inhibator
Alpha 4 inhibator

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3
Q

What drug class is Balsalazide

A

5-ASA

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4
Q

What is the structure of balsalzide

A

Inert carrier and 5-ASA

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5
Q

What drug class is sulfsalazine

A

5-ASA

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6
Q

What is the structure of Sulfasalazine

A

5-ASA with sulfapyridine

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7
Q

What is the route of administration for Ustekinumab for maintenance

A

SubQ

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8
Q

What is the route of administration for Ustekinumab for induction

A

IV single infusion

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9
Q

What drug class is Golimumab

A

TNF inhibator

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10
Q

What is infliximab used to treat and how is it administered

A

Moderate to severe UC and CD

-IV every 8 weeks

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11
Q

What is Tofacitinib used to treat and how is it administered

A

Moderate to severe UC

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12
Q

What is the structure of Olsalazine

A

2 molecules of 5-ASA

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13
Q

What are the drugs that can be given for Crohn disease

A

IL12/23 inhibators
TNF alpha inhibitors
Alpha-4 inhibators

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14
Q

Alpha 4 integrin inhibators have which severe complication associated

A

Progressive multifocal leukoencephalopathy

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15
Q

What drug class is Tofacitinib

A

JAK inhibators

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16
Q

What is the structure of Mesalamine

A

Single 5-ASA

17
Q

What drug class is Mesalamine

A

5-ASA

18
Q

What drug class is alpha4 integrin inhibator

A

Vedolizumab

19
Q

What is the drug Balsalazide used to treat

A

Only for active UC in males

20
Q

Which TNF inhibitor is different than the others with regard to structure

A

All are IgG antibodies except certolizumab, which is a Fab

21
Q

What drug class is natalizumab

A

Alpha 4 integrin inhibator

22
Q

What drug class is Inflizimab

A

TNF inhibator

23
Q

What drug class is ustekinumab

A

IL12/23 inhibator

24
Q

What is golimumab used to treat and how is it administered

A

Moderate to severe UC only

-SubQ every 4 weeks

25
Q

What drug class is infliximab

A

TNF inhibitor

26
Q

What is the certolizumab used to treat and how is it administered

A

Moderate to severe CD only

SuqQ every 4

27
Q

What are 5-ASA agents used to treat, and which are the exceptions

A

Mild to moderate UC

  • Olsalazine
  • Balsalazide
28
Q

What is Natalizumab used to treat and how is it administered

A

Moderate to sever CD

-IV every 4 weeks

29
Q

What is adalimumab used to treat and how is it administered

A

Moderate to severe UC and CD

SubQ every 2 weeks

30
Q

What is vedolizumab used to treat and how is it administered

A

Moderate to severe CD or UC

-IV every 8 weeks

31
Q

What is the drug Olsalazine used to treat

A

Maintenance of UC

32
Q

What drug class is certolizumab

A

TNF inhibator

33
Q

What is IL-12/23 inhibitors used to treat

A

Moderate to severe CD

34
Q

What drug class is TNF- inhibators

A

Adalimumab

Pharmacology & Drugs (43 decks)

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