GI- IBD Drugs Flashcards
What drug class is Olsalazine
5-ASA
What are the classes of drugs that can be given for UC
-5-ASA
JAK inhibator
TNF inhibator
Alpha 4 inhibator
What drug class is Balsalazide
5-ASA
What is the structure of balsalzide
Inert carrier and 5-ASA
What drug class is sulfsalazine
5-ASA
What is the structure of Sulfasalazine
5-ASA with sulfapyridine
What is the route of administration for Ustekinumab for maintenance
SubQ
What is the route of administration for Ustekinumab for induction
IV single infusion
What drug class is Golimumab
TNF inhibator
What is infliximab used to treat and how is it administered
Moderate to severe UC and CD
-IV every 8 weeks
What is Tofacitinib used to treat and how is it administered
Moderate to severe UC
What is the structure of Olsalazine
2 molecules of 5-ASA
What are the drugs that can be given for Crohn disease
IL12/23 inhibators
TNF alpha inhibitors
Alpha-4 inhibators
Alpha 4 integrin inhibators have which severe complication associated
Progressive multifocal leukoencephalopathy
What drug class is Tofacitinib
JAK inhibators
What is the structure of Mesalamine
Single 5-ASA
What drug class is Mesalamine
5-ASA
What drug class is alpha4 integrin inhibator
Vedolizumab
What is the drug Balsalazide used to treat
Only for active UC in males
Which TNF inhibitor is different than the others with regard to structure
All are IgG antibodies except certolizumab, which is a Fab
What drug class is natalizumab
Alpha 4 integrin inhibator
What drug class is Inflizimab
TNF inhibator
What drug class is ustekinumab
IL12/23 inhibator
What is golimumab used to treat and how is it administered
Moderate to severe UC only
-SubQ every 4 weeks
What drug class is infliximab
TNF inhibitor
What is the certolizumab used to treat and how is it administered
Moderate to severe CD only
SuqQ every 4
What are 5-ASA agents used to treat, and which are the exceptions
Mild to moderate UC
- Olsalazine
- Balsalazide
What is Natalizumab used to treat and how is it administered
Moderate to sever CD
-IV every 4 weeks
What is adalimumab used to treat and how is it administered
Moderate to severe UC and CD
SubQ every 2 weeks
What is vedolizumab used to treat and how is it administered
Moderate to severe CD or UC
-IV every 8 weeks
What is the drug Olsalazine used to treat
Maintenance of UC
What drug class is certolizumab
TNF inhibator
What is IL-12/23 inhibitors used to treat
Moderate to severe CD
What drug class is TNF- inhibators
Adalimumab
