Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Pharmacology & Drugs > GI-Diarrhea And Abdominal Pain > Flashcards

GI-Diarrhea And Abdominal Pain Flashcards

1
Q

What drug class is diphenoxylate

A

Opioid agonists

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What is a severe side effect of alosetron and what is the sign that it may occur

A

Ischemic colitis is a severe complication, and is indicated by a patient developing constipation (especially since the drug was given to a pt with diarrhea)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What drug class is lubiprostone

A

Selective chloride channel activator

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What drug class is bisacodyl

A

Stimulant laxitive

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What drug class is crofelemer

A

Chloride channel inhibitors

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What conditions are treated with lubiprostone

A
  • IBS-C
  • chronic idiopathic constipation (CIC)
  • Opioid induced constipation (OIC)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What is castor oil hydrolized to

A

Ricinoleic acid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What drug class is alosetron

A

5 HT antagonists

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What drug class is naloxegol

A

Opioid antagonist

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What is the mechanism of action for guanylate cyclase G agonist

A

Increases cGMP leading so secretion of chloride and bicarbonate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Which patients need extra monitoring when on eluxadoline

A

Those without gallbladders at risk for pancreatitis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What drug class is glycerin

A

Stimulant laxitve

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What drug class is dicylomine

A

Antimuscarinic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What drug class is chlordiazepoxide

A

Antimuscarinic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What is guanylate cyclase C agonists used to treat

A

Constipation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What is the drug class opioid agonists used to treat

A

Diarrhea

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Which conditions are treated with Linaclotide

A

IBS- constipation

Chronic idiopathic constipation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

What is the drug class 5HT antagonists used to treat

A

Diarrhea

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

What drug class is alvimopan

A

Opioid antagonists

20
Q

What drug class is hyoscyamine

A

Antimuscarinic

21
Q

What is the indication for eluxadoline

A

IBS-diarrheal subtype (IBS-D)

22
Q

What drug class is methylnaltrexone

A

Opioid antagonist

23
Q

What drug class is senna

A

Stimulant laxitive

24
Q

What drug class is loperamide

A

Opioid agonists

25
Q

What is the source of crofelemer

A

Sap from croton lechleri

26
Q

What is sodium picosulfate used for

A

Precolonoscopy

27
Q

What is the drug class prostaglandin inhibators used to treat

A

Diarrhea

28
Q

What is the mechanism of action of stimulants

A

Aka irritants and actually aggregate the lining to increase motility

29
Q

What drug class is Eluxadoine

A

Opioid agonists

30
Q

What is the complication seen with alvimopan

A

Risk of MI

31
Q

What are the contraindications for eluxadoline

A
  • Biliary tract infection and bile issues
  • Panceratic issues
  • liver failure
  • alcoholism
32
Q

What are selective Chloride channel activators used to treat

A

Constipation

33
Q

What drug class is castor oil

A

Stimulant laxitive

34
Q

What are the side effects of treatment of antimuscarinic in IBS patients

A

Anticholinergic effects (DUMBBELLS)

35
Q

What drug class is bismuth

A

Prostaglandin inhibators

36
Q

What is the drug class chloride channel inhibitors used to treat

A

Diarrhea

37
Q

When is alosetron used

A

Chronic sever, IBS-diarrheal is not responsive to other therapies (especially in women)

38
Q

What drug class is clidinium

A

Antimuscarinic

39
Q

What is the mechanism of action for lubiprostone

A

Increases the secretion by activating chloride channels CIC-2 in luminal epithelium

40
Q

Which patients are given crofelemer

A

Non-infectious Diarrhea in HIV and AIDs patients with anti-retroviral therapy

41
Q

When is Alvimopan used

A

Accelerating time in GI recovery following bowel surgery and prevention of ileus

42
Q

What are the antimuscarinic agents given for

A

Abdominal pain/IBS

43
Q

What drug class is linaclotide

A

Guanylate Cyclase C agonists

44
Q

What must be given with diphenooxylate and what is the reasoning

A

Class 5 drug opiate, given with atropine for abuse potential

45
Q

What drug class is calcium polycarbophil

A

Bulk forming cathartic

Pharmacology & Drugs (43 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions