Respiration: Ventilation (V), Perfusion (Q) & V/Q Relationship Flashcards

1
Q

What is ventilation?

A

Process by which air moves in and out
of lung.

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2
Q

What is perfusion?

A

Process by which deoxygenated blood
passes through the lung and becomes oxygenated

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3
Q

Why is ventilation not uniformly distributed in the lungs?

A

Gravity

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4
Q

What does the term compliance refer to?

A

How much effort is required to stretch the lungs and chest wall

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5
Q

When is decreased compliance common?

A

In pulmonary conditions such as tuberculosis

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6
Q

What does resistance refer to?

A

Narrowing or obstruction of the airway that my reduce
airflow.

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7
Q

When is increased resistance common?

A

In pulmonary conditions such as asthma and COPD

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8
Q

What is anatomical dead space?

A

Volume of gas during each breath that fills the conducting airways.

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9
Q

What is physiological dead space?

A

Total volume of gas in each breath that does not participate in gas exchange, e.g., alveoli that are perfused but not ventilated.

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10
Q

How do you calculate the V/Q ratio for the entire lung?

A

Alveolar ventilation / cardiac output

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11
Q

What is the average V/Q ratio of the entire lung for a healthy individual?

A

0.8-1.2

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12
Q

What is arterial hypoxemia?

A

When the partial pressure of arterial o2 is less than 80mmHg

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13
Q

What is an anatomical shunt?

A

The blood taken in by the pulmonary artery doesn’t become deoxygenated. This means the blood being delivered to rest of body is dilated, effecting PO2

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14
Q

When are anatomical shunts common?

A

In babies at a cardiac level

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15
Q

What is a physiological shunt?

A

When the ventilation to the lung is absent, effecting the po2 leaving the lung. The alveolar sac is blocked

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16
Q

What could a physiological stunt be caused by?

A

Mucous plugs
Oedema
Foreign bodies
Tumours

17
Q

What is COPD?

A

A condition where airflow is obstructed due to narrowing lumen for air to flow

18
Q

What is pulmonary fibrosis?

A

Condition where lung tissue is thickened and scarred, the elasticity is decreased. Patients usually die within 4 years