Pain Flashcards

1
Q

What is normal pain known as?

A

Acute Nociceptive pain

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2
Q

What axon corresponds to sharp stabbing pain?

A

A DELTA

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3
Q

What fibres are responsible for dull aching pain?

A

C fibres

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4
Q

What type of receptor endings do nociceptors have?

A

Free nerve endings

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5
Q

What part of the spinal chord do A DELTA or C fibres go into during the spinothalamic pathway?

A

Outer layers of dorsal horn

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6
Q

What area does the second order pain projecting neurons move to in the spinal chord?

A

The other side of the body to the antero-lateral funiculus

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7
Q

What other parts of the brain does the second order neuron activate on its way to the thalamus in spinothalamic pathway?

A

Medulla
Pons
Midbrain
This is known as the spinal lemniscus

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8
Q

Where does the first order neuron synapse with the secondary neuron during Ventral trigeminothalamic pathway?

A

The spinal nucleus in the spinal chord which crosses the midline

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9
Q

What are the 2 pain pathways?

A

Spinothalamic (body)
Ventral trigemino-thalamic pathway (face)

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10
Q

How can the location of pain be misleading?

A

When talking about referred pain

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11
Q

What is referred pain?

A

Pain perceived on one part of the body but the pathology is elsewhere

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12
Q

Why can some people not recruit pain fibres?

A

Loss of Nav1.7 function

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13
Q

What are some physiological factors which can effect pain?

A

Sex
Age
Previous pains
Family
Culture

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14
Q

What are emotional factors which effect pain?

A

Fear
Anger
Frustration

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15
Q

What is does the gate control theory of pain suggest?

A

Inhibitory inter neurons block perception of pain as they are released when a rubbing action initiates A DELTA fibres

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16
Q

What do the descending nerves from the pain pathways do?

A

Modulate the pain

17
Q

What does the supraspinal loop do?

A

Modulates the pain

18
Q

What is the triple response include?

A

Red reaction
Wheal
Flare

19
Q

What is dermatographia?

A

When you can write/draw on skin

20
Q

What does bradykinin promote?

A

Inflammation

21
Q

What does the release of substance p and CGRP do within the pain pathway?

A

Mast cells to area to degranulate histamine
Release of bradykinin
Dilation of blood vessels

22
Q

What are relieving factors to the triple response?

A

Cold water pressure
Anti-histamine , reduces degranulation