Resp path II Flashcards
contavious bovine pleuropneumonia cause
mycoplasma mycoides spp. mycoides (small colony type)
pleuropneumonia gross histo
- unilateral, cd lung lobe
- marbled apperance
- fibrinous pleuritis/ adhesions
- pleural effusion
differential diagnosis bovine pleuropneumonia
- mannheimia haemolytica
- mycoplasma mycoides spp. mycoides
contagious bovine pleuropneumonia sequestrum
- necrosis secondary to loss of vascular supply
contagious caprine pleuropneumonia cause
- mycoplasma capricolum spp. capripneumoniae
mycoplasma capricolum spp. capripneumoniae contagious caprine pleuropneumonia -> ?
- high mortality
- fibrinous pleuropneumonia
- multifocal necrosis
interstitial pneumonia spread type/ general cause
- aerogenous or hematogenous spread
- most often viral cause
causes porcine interstitial pneumonia
viral - swine influenze - PRRSV - PCV-2 - PRCV - Pseudorabies bacterial (sepsis) - Salmonella choleraseuis - Haemophilus parasuis
swine influenza virus -> clinical presentation and dx
dx - porcine interstitial pneumonia clinical signs -high morbidity - resp signs
swine influenza what type virus/ swine receptos
- segmnted ss RNA
- pig has receptors for human and avian strains
- pt of porcine resp dx complex
porcine interstitial pneumonia histo/ necropsy
- diffuse pattern in lungs
- edema
- airway epithelium damage
necrosis of swine airway differntials
- porcine interstitial pneumonia
- bovine herpes virus 1
porcine reproductive and respiratory syndrome virus (PRRSV) -> ?
- porcine interstitial pneumonia
- target or damage PAM/PIM
- > secondary bacterial bronchopneumonia and sepsis
porcine circovirus type 2 (PCV-2) -> what concurrent with what
porcine respiratory and reproductive syndrome virus
histo of pcv-2 vs porcine respiratory and reproductive syndrome virus
circoviridae see granulomatous inflam
pcv-2 see what
- porcine interstitial pneumonia
- granulomatous infla
- icterus
- enlarged lymph nodes
nipha virus pig can ->
- interstitial pneumonia
- resp and cns dx
- ZOONOTIC
nipha virus genus and fam
- genus= henipavirus
- fam= paramyxoviridae
hendra virus equine genus and fam
- genus= henipavirus
- fam= paramyxoviridae
- ZOONOTIC*
Equine hendra virus -> ?
- interstitial pneumonia
- see massive pulmonary edema
small ruminant lentiviruses include
- ovine progressive pneumonia (OPP)
- caprine arthritis and encephalitis (CAE)
lentiviruses features of dx type
- non-oncogenic/ non-immunosuppressive
- main targets = monocytes, macrophages, dendritic cells
- > chronic inflam
small ruminant lentiviruses pathogeneisis
- acute dx
- chronic dx = slow progressive multi-organ lymphoproliferative fatal dx
- see interstitial fibrosis
ovine progressive pneumonia caused by what
lentivirus
ovine progressive pneumonia see what
- arthritis/ synovial hyperplasia
- mastitis
- lymphadenopathy
- resp dx w/ diffuse lung involvement
ovine progressive pneumonia spread
- widespread infection/ rare clinical dx
ovine progressive pneumonia see clinical dx in who
- older animals
caprine arthritis and encephalitis cause
lentivirus
caprine arthritis and encephalitis see what
- interstitial pneumonia similar to OPP
enzootic nasal tumor virus
-> ?
- sheep ENTV-1
- goat ENTV-2
- Nasal adenoma -> carcinoma rarely metastasizes
sheep: retrovirus-induced ovine pulmonary adenocarcinoma (OPA) see what grossly
- areas neoplasia replace lung parenchyma w/ firm white fibrotic neoplastic lesions
jaagsiekte sheep retrovirus virus causes what
neoplastic change inland keeps growing until large portion of lung affected (looks like opa)
granulomatous interstitial pneumonia occurs how
organisms or particles -> resist intracellular killing by phagocytic cells -> persist and cause chronic granulomatous inflammation response
granulomatous interstitial pneumonia include
- bovine pulmonary tuberculosis
- granulomatous/ pyogranulomatous pneumonia horse
- FIP
bovine pulmonary tuberculosis is caused by what
- mycobacterium bovis
- zoonotic
mycobacterium bovis bovine pulmonary tuberculosis signs
- lung granulomas (tubercles); multifocal variably sized accesses in cd lung goes
- lymph node involvement (accesses in ln)
- +/- mineralization
what causes caseous accesses in lungs (pathogens)
- mycobacterium bovis
- trueparella pyogeneis
mycobacterium bovis vs trueparella staining
- mycobacterium are acid fast trueparella is not
mycobacterium tuberculosis affects who
- human beings (only reservoir host)
- dogs and cats are susceptible
dogs= respiratory
cats = enteric
granulomatous/ pyogranulomatous pneumonia cause horse
rhodococcus equi
- may have multiple small granulomatous lesions not just one larger lesion
- in foal 1-6 months this = primary differential, can look like trueparella and mycobacterium but in foal look at this first*
feline infectious peritonitis -> what kind of lesions
- granulomatous lesions throughout lungs
- can have lesions on other organs as well
interstitial pneumonia primary mycotic agents multifocal and granulomatous
- blastomyces dermatidis
- nocardia asteroides/ nova
- cryptococcus neoformans
- coccidiodes immitis
- pneumocystis carnii
canine blastomycoidis caused by what
blastomyces dermatitis
canine blastomycoides affects who
dogs and humans rare in other domestic aniamls
canine blastomycosis see what
- pyogranulomatous interstitial pneumonia w/ diffuse patterns through lungs
- broad based budding coccidian mycosis= broad-based budding yeast
blastomyces dermatitis -> what kind of mycosis; form and infections phase
systemic mycosis
- dimorphic fungus
- gross as yeast phase = non- infectious
- hematogenous and lymphatic dissemination
cutaneous form
- penetrating wound
pulmonary coccidiomycosis affects who
- camelids > horses
pulmonary coccidiomycosis caustitive agent
coccidiodes immitus
ZOONOTIC
pulmonary coccidiomycosis see what dx
pyogranulomatous interstitial pneumonia
pneumocystis carinii seen in who
- pig
- horse
pneumocystis carinii what type of infection
opportunistic fungal infection
interstitial pneumonia parasitic causes
lung resident parasits
- nematodes adult/ larvae in airways/ alveoli
- metacestode lungs of intermediate host
lung- migrating parasits
- larva migrans
- flukes
embolic pneumonia spread how
hematogenous spread from elsewhere
- fungal
- bacterial
emobolic pneumonia presentation
- multifocal- random- all lobes
fungal causes embolic pneumonia
aspergillis spp.
bacterial causes embolic pneumonia
- trueperella pyogenes
- fusobacterium necrophorum
pulmonary aspergillosis -> what in horse
- embolic fungal pneumonia horse
- enteritis/ colitis/ typhilitis = open door for fungus to enter lung
salmonella enterocolitis horse -> what
embolic fungal pneumonia horse
- disruption of intestinal barrier
- hematogenous spread
- localization to other organs - liver/ lungs
embolic fungal pneumonia horse differentials
- pulmonary aspergillosis
- salmonella enterocolitis
embolic fungal pneumonia horse signs
- necrosuppurative inflam
- mass of fungal hyphae
- vasculitis/ thrombosis
embolic pneumonia cattle causes
- pulmonary septic embolism- hematogenous
aspiration pneumonia lesions
- focal necrohemorrhagic pneumonia (one lobe)
- foreign body aspriation
- necrosis
- hemorrhage
- inflammation
