Proteins and Permeability Flashcards

1
Q

what are the six major functions of membrane protein?

A

1) transport
2) Enzymatic activity
3) Cell to cell recognition
4) Attachment to cytoskeleton & Extra-cellular matrix
5) Single transduction
6) Intracellular joining

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2
Q

What moelcules have some permeability?

A

Some permeability to water molecules and small uncharged molecules like carbon dioxide and oxygen

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3
Q

What molecules aren’t permeable?

A

ions, K+,CA 2+,NA +, Cl-, HCO3-, small hydrophilic molecules, macromolecules (protein/RNA) and sugar (fructose and glucose)

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4
Q

What is diffusion?

A

Due to random motion over time, molecules become more equally distributed, no energy is required. It eliminates a con. gradient so molecules can cross

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5
Q

What is osmosis?

A

Diffusion of water through a selectively permeable membrane from an area of low con. into an aqueous compartment containing absolute at a higher concentration (across)

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6
Q

When does osmosis occur?

A

It occurs when a solute cannot cross the cell membrane, so the water moves instead

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7
Q

Passive transportation

A

moves from an area with a high con, to an area with low con.

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8
Q

What is facilitated diffusion?

A

Passive transport aided by proteins, down the con. gradient via transport protein

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9
Q

What is active transport?

A

Sodium and potassium pump moves ions against their con. gradient ( requires energy)
Lower con –> to a higher con.
USES ATP

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10
Q

Co transport?

A

sodium and glucose ions move into the cell through a co-transporter protein glucose with and sodium against

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11
Q

Osmotica and osmolarity

A

Glucose stays the same, ions break up, if you have two times then add together

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12
Q

Questions to ask doing osmolarity Qs

A

1) can the solute cross the membrane w/passive diffusion (it doesn’t count)
2) osmosis
3) When a solute dissolves, does a molecule stay together or split into ions?

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13
Q

Osmolarity =?

A

(osm/L)= molar con X no. moles or ions in solution

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14
Q

What is the tonicity?

A

The ability of a solution to cause a cell to gain/loose water

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15
Q

Define isotonic?

A

Solution concentration is the same as the inside of the cell, no net water movement across the plasma membrane.

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16
Q

Define hypertonic?

A

Solution concentration is greater than that inside the cell; the cell loses water (shrivel)

17
Q

Define hypotonic?

A

solution concentration is less than that inside of the cell; the cell gains water (lysed)

18
Q

Hypotonic in plants?

A

Turgid

19
Q

Isotonic in plants?

A

Flaccid

20
Q

Hypertonic in plants

A

Plasmolysed

21
Q

1 M =?

A

1000 mM