DNA Flashcards
What do the size and shape of the bases show?
The shapes and sizes of the Nitrogenous bases help us understand why the GC and AT pairs exist in DNA
G &C have 2 rings
A,T and U have 1 ring
What are base pairings held by?
Base pairings are held together by weak H2 bonds and they are easy to break
GC- 3 bonds
AT- 2 bonds
What is the process of DNA replication?
1) parent strand has 2 strands of DNA, each base is paired by hydrogen bonding
2) The 2 DNA strands are separated, each strand can be a template
3) nucleotides complementary to the parent strand are connected to form sugar, phosphate backbone
Order
5’ 3’
3’ 5’
What does the old strand do to mark the original strand?
The cell tags the old strand with methylate, then the enzymes scan for mistakes
What is the first step in replication?
1) The helicase unwinds and separates the parental DNA strands
What is the second step?
2) single-strand binding proteins stabilise the unwound parental strands
What is the third step in replication?
Topoisomerase breaks down, swivels and rejoins the DNA ahead of the replication fork and relives stress
What is the fourth step in replication?
Primase synthesises the RNA primers using the parental DNA as a template