DNA Flashcards

1
Q

What do the size and shape of the bases show?

A

The shapes and sizes of the Nitrogenous bases help us understand why the GC and AT pairs exist in DNA
G &C have 2 rings
A,T and U have 1 ring

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2
Q

What are base pairings held by?

A

Base pairings are held together by weak H2 bonds and they are easy to break
GC- 3 bonds
AT- 2 bonds

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3
Q

What is the process of DNA replication?

A

1) parent strand has 2 strands of DNA, each base is paired by hydrogen bonding
2) The 2 DNA strands are separated, each strand can be a template
3) nucleotides complementary to the parent strand are connected to form sugar, phosphate backbone

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4
Q

Order

A

5’ 3’

3’ 5’

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5
Q

What does the old strand do to mark the original strand?

A

The cell tags the old strand with methylate, then the enzymes scan for mistakes

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6
Q

What is the first step in replication?

A

1) The helicase unwinds and separates the parental DNA strands

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7
Q

What is the second step?

A

2) single-strand binding proteins stabilise the unwound parental strands

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8
Q

What is the third step in replication?

A

Topoisomerase breaks down, swivels and rejoins the DNA ahead of the replication fork and relives stress

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9
Q

What is the fourth step in replication?

A

Primase synthesises the RNA primers using the parental DNA as a template

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