Protein Structure and Function Pt1

Question 1

8 types of proteins

Answer 1

Structural proteins
Enzymes
Transport proteins
Storage proteins
Motor proteins
Receptor proteins
Signal proteins
Hehe regulatory proteins

Question 2

What catalyses peptide bonds?

Answer 2

Ribosomes (ribozyme)

Question 3

What are smaller polypeptides called?

Answer 3

Oligopeptides and peptides
AA sequence affects protein structure

Question 4

Where does peptide bond formation take place?

Answer 4

At the carboxyl or amino group of the amino acid

Question 5

What gives an amino acid its unique properties?

Answer 5

The R group does depending on the side chains such as acidic,basic, uncharged, or non polar

Question 6

What is the pKa

Answer 6

It’s the acid dissociation constant that describes the acidity of a particular molecule

Dissociation of carboxyl and amino groups

(H+ given off or added)

Question 7

What is the isoelectric point (pI)?

Answer 7

It’s the pH where the amino acid has no net electrical charge (where it is neutral)

Question 8

Describe the backbone of the peptide

Answer 8

The peptide bond is rigid and planar and C-N bond inflexible

Question 9

What’s bonds are involved in protein folding?

Answer 9

Covalent bonds such as disulphide bridge bond and many weak non covalent bonds such as ionic bonds, H bonds, VDW bonds.

Question 10

Misfolded proteins can lead to diseases, what helps with protein folding?

Answer 10

Chaperone proteins help with folding