Microbiology L3 And L4 Flashcards

1
Q

Innate and adaptive immune systems work together

A

Interferon proteins released to interfere with the viral mRNA and inhibit protein translation in infected and surrounding cells

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2
Q

Cytotoxic cells release granzymes and perforin to trigger apoptosis in cancerous cells or those infected with bacteria or virus

A

So they bind release kill cell kinda like pirate ship wars

Mediated by CD8 and T cells

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3
Q

Two types of T cells

A

Cytotoxic cd8 T cell kill using chemicals

Helper cd4 T cell synthesise and secrete signalling molecules for inflammation and activate B cells and T cytotoxic cells

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4
Q

HIV two identical strands of rna enclosed in core

A

HIV is known as a retrovirus and fuses with host cell

Contains reverse transcriptase

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5
Q

Three stages of hiv infection

A

First stage is acute retroviral syndrome
A week or two of feeling ill then it goes away

Second stage is chronic HIV infection asymptomatic this stage can last 10 years or more
During this time hiv kills t helper cells

Third stage AIDS when helper cells under 200
Can also have aids if you have kaposi sarcoma or pneumonia

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