Pharmokinetics Flashcards
1
Q
ADME what does it stand for?
A
Absorption
Distribution
Metabolism
Elimination
2
Q
3 types of administrating a drug
A
Enteral routes -asshole oral
Parenteral routes - iv injecting
Per cutaneous- through skin or membrane like cream or inhaler
3
Q
What does administration depend on?
A
Route of administration
Blood flow at the site
Drug solubility
4
Q
What does distribution depend on?
A
Blood flow and lipid solubility and diffusion barriers
And plasma protein binding
5
Q
Blood brain barrier consists of
A
Tight junctions small pores and less of them and reduced capillary permeability
6
Q
Lipid insoluble drugs do not enter the brain and more for plasma
A
Lipid soluble drugs do enter the brain and can access everything
7
Q
How do we measure distribution?
A
Radio tracer studies and volume of distribution
