polio Flashcards
moa
aerosol
fecal oral route
main countries
pakistan and afghanistan
receptor affinity
cd 155 in anterior spinal horns and DRG
ip
5- 35 days
vaccination programme
2 months deffo
3 months deff
4 months
buzz word for polio
asymmetric!
how many types and explain
1 - most likly to lead to outbreak
2 - eradiacted in 1999
3- hardest to be eradicated
forms
spinal - most common and asymmetric
bulbar- affects CN, dysphagia etc nasal speech especially those of the soft palate
spinobulbar - combination
symptoms
most people are asymptomatic !
muscle pain
meningeal symptoms- enteroviruses are the most common causes of viral meningitis
gi- as enterovirus either constipated or diarrhea (most likley)
loss of reflexes
sore throat
paralysis - may persist if the anterior cells are completely destroyed
severe- mechanical ventilation as diapghargms stops
post plio syndome a non-contagious condition that can affect polio survivors usually 15 to 40 years after recovery from polio
post polio syndrome a non-contagious condition that can affect polio survivors usually >15 years after recovery from polio
- fatigue
-atrophic muscles - muscle pain
- sleep apnea
The symptoms tend to get gradually worse over many years, but this happens very slowly and treatment may help slow it down further.
The leading theory is that it’s the result of the gradual deterioration of nerve cells in the spinal cord (motor neurones) that were damaged by the polio virus. This would explain why the condition can take years to appear.
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