infectious mono

Question 1

cause

Answer 1

EBV( HH4) is the main cause but other viruses can cause

hepatitis
adenovirus
HIV

Question 2

MOA

Answer 2

body secretions mainly saliva- sharing cups etc but other body fluids too like seman, blood

Question 3

epi

Answer 3

15-25 year olds, (where we mostly observe active infection ) young kids usually asymptomatic/mild approximately 90% adults are sero+

Question 4

main symptoms

Answer 4

fever, pharygitis ,tonsilitis (can make it heard to breathe) lympadenopathy, (cervical) hepatospelonemgaly

Question 5

IP

Answer 5

4- 6 weeks or 1/2 months

Question 6

tx

Answer 6

usually supportive - because its self limiting so fluids, rehydration !
as the spleen can grow very large avoid physical activity for 3 weeks after

Question 7

complications

Answer 7

rupture spleen
aplastic anemia
increased risk of H lymphoma

Question 8

diagnosis

Answer 8

serology ‘heterophile ab’
atypical lymphocytes- the nucleus and a lot of cytoplasm
liver enzymes-exclude liver involvement

Question 9

key target of infection

Answer 9

b lymphocytes

Question 10

whats not recommed to give to mono

Answer 10

penicillin because it leads to a rash