brucellosislla

Question 1

moa

Answer 1

contact with infected animals
ingestion unpasteurised milk
exposure to infected bodily fluids - animals giving birth

most common is drinking the meat

but also can breathe in bacteria

Question 2

mb

Answer 2

gram - intracellular coccobaccili

Question 3

pathogens

Answer 3

gets taken up by macrophages survives inside and macrophages take it to the lymphatics to be cleared

Question 4

symptoms

Answer 4

constitutional symptoms
fever - common cause of fever of unknown origin . the fevr is often worse at night !!!!
night sweats - charctaeirstic moldy odour
weight loss

and other flu like

in some patients inability to clear the organism causes granulomas to form (in lN)

physical signs
heptaosplenomegaly -
lympahdenopathy
the bug has a propensity to go to the heart so you may hear a heart murmurs

genitourinary symptomes - epididymitis, orhcitis

Question 5

diagnosi

Answer 5

serology
serodiagnosis

Question 6

tx

Answer 6

not pregnant - doxycycline + often combined with gentamicin or streptomycin
pregnant - rifampin

Question 7

species

Answer 7

Brucella melitensis (goats)- high pathogenicity
• Brucella abortus (causes abortions in cows) • Brucella suis (pigs)- high pathogentiicty
• Brucella canis (dogs)

Question 8

prophylaxis

Answer 8

pasteurisation of
protective gear for animal handlers gloves, goggles

there’s a vaccine for animals

Question 9

which type is more virulent

Answer 9

B melitensis is thought to be the most virulent and causes the most severe and acute cases of brucellosis; it is also the most prevalent worldwide

Question 10

whats the danger

Answer 10

bioloigcal warefare