hemorrgaic fevers overview Flashcards
dic
found in any severely ill patient but is thought to occur more regularly in crimean Congo hemorrhagic fever and HFRS
specific organs
In some viral HF, specific organs may be particularly impaired, such as: the kidney in haemorrhagic fever with renal syndrome (HFRS, the lung in hantavirus pulmonary syndrome, and the liver in yellow fever BUT IN ALL HF’S the generalilised circulatory disturbance is cortically important
general features
starts as a flu like illness that rapidly progresses to a systemic illness and fatality rates can be 90%
pharangyeal hyperaemia
conjunctival suffusion
cutaneous flushing
chest pain + abdo pain
classes of virus
arena
filo
flavi
bunya
bunya category
hanta virus +Rift Valley
arena virus category
lassa fever
fill category
ebola + marking
main pathogenetic factors
damage to the vascular system
pro inflammatory cytokines
damage to target organ
general labs
increase liver enzymes
plT down
pt elevated
hemoconcetration from leakage (most marked in hanta virus + dengue shock syndrome
diagnosis
- rt- pcr first
- elisa
dx
malaria, thyphoid
Overwhelming parasitaemia/ septicaemia may produce a similar clinical picture and require to be excluded, eg. meningococcus, snake bite, tryponosomiasis
HFRS labs
- proteinurie
- LEUKOCYTOSIS
- hyposthenuria
- thrombocytopenia
treatment for HFRS
ribarin (remember same for CCHF)
SEVERE FORE OF HFRS
a lot of eye issue, hurt to move the eyes
photophobia and can develop blurry vision
Petechiae develop on the 3rd to 5th day, initially on the palate, then at pressure areas such as the axillary folds.
costovertebral tenderness= retripetiotoneal edema
name of severe form of HFRS
korean H fever or that seen in the balkans
hanta virus pulmonary syndrome example
sin nombre virus which infects the deer mouse
what’s unique of pulmonary syndrome
he conjunctival and cutaneous signs of vascular involvement seen in other types of HF are absent!!
izziness is common and vertigo occasional
symptoms of pulmonary
non cariogenic pulmonary edema
hypotension - which is why in treatment you don’t want to give too much aggressive fluids as you have bradicardia
West Nile virus is part of
same family as dengue + yellow spread by mosquitoes from birds
which is called break bone fever
because of the painful backache, muscle and joint pain, and severe headache. Painful fever!
IP YELLOW FEVER
3-6 days
who critreria for dengue
FEVeR
HEMORRHAGIC MANIFESTATIONS
HEPATOMEGALY
THROMBOCYTOPENIA
HCT - increased by 20 %
KEY buzzord for dengue
- retrorbotal pain
IP dengue
4-10 days
