Perturbational methods Flashcards
Perturbational methods
Change workings of the brain, making causal relation between changes in brain and behaviour possible
Types that fall under perturbation
Brain lesions
Pharmacological
Brain stimulation
Brain lesions
Damage to the brain as a result of eg stroke, or case like gage
+ Gives lot of insight
- Single case studies
- Not under control of experimenter (not focal)
- Difficult to generalize, no two are the same and can be caused by many areas.
Pharmalogical
Seeing how drugs interfere with brain (addicts or experimentally controlled)
Agonist and antagonist
Bromoaptine eg is an agonist, does the same as real dopamine. Antagonist binds to receptor but blocks it.
- Very unspecific, effects whole brain
Brain stimulation intracranial
Electrical stimulation by implanting electrode in eg subthalamic nucleus, or eg optogenetics where light gated ion channels are implanted.
Brain stimulation extracranial
TMS: Magnetic field causing neural activity. Can be single pulse or repetitive (longer). Temp resolution is high but spatial very low
TES: aka tDCS, small current placed directly onto scalp. NOT neural