Peptic Ulcer disease Flashcards

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1
Q

what is the prevalence of peptic ulcer disease?

A

aprox 10 % incidence (significant prevalence)

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2
Q

what is peptic ulcer disease

A
  • ulcerative disorder of upper & GI tract
  • 20% happens in stomach
  • 80% duodenum
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3
Q

what layer of intestine does peptic ulcer disease primarily affect

A

-primarily affects mucosa

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4
Q

what is the protective factor of the stomach

A

stomach has mucus barrier to protect from HCL

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5
Q

what is the protective factor of the duodenum

A

duodenum has pancreatic buffer to protect from, if HCL comes in when no pancreatic buffer (from pancreatic juices) affecting negatively

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6
Q

what is the pattern that peptic ulcer disease comes in

A

pattern of remissions & exacerbations

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7
Q

what is the etiology of peptic ulcer disease

A
  • helicobacter pylori infection (bacterial infection) (not normal bacteria in the gut) : -site
    - adhesion
    - Urease
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