P8 PATHOLOGY

Question 1

mention the factors affecting the donor’s eligibility

Answer 1

• the health of the donor
• the safety , purity , quality of the blood

Question 2

the age of the donor should be between

Answer 2

17 - 65 years

Question 3

the minimum donation interval is

Answer 3

12 weeks

Question 4

a donor who gives blood when required to family members or community is known as

Answer 4

family / replacement blood donor

Question 5

a donor who gives blood to be stored &. re-infused when required is known as

Answer 5

Autologous blood donor

Question 6

a donor who donates only one of their blood components through process of cell separation is known as

Answer 6

Apheresis donor

Question 7

a person who donates unwillingly is known as

Answer 7

forced blood donor

Question 8

Mention 4 transfusion-transmissible infectious agents

Answer 8

• HIV
• HBV
  -HCV
• Treponema pallidum

Question 9

red cells can be stored up until

Answer 9

42 days

Question 10

fresh frozen plasma & cryoprecipitate can be stored up to

Answer 10

up to 1 year

Question 10

Platelets can be stored up to

Answer 10

5 days

Question 11

Antibodies for group A RBC type

Answer 11

anti-B

Question 12

Antibodies for group B RBC type

Answer 12

ANti- A

Question 13

Antibodies for group AB RBC type

Answer 13

none

Question 14

Antibodies for group O RBC type

Answer 14

anti-A & anti-B

Question 15

Antigens in group A RBC

Answer 15

A antigen

Question 16

Antigens in group B RBC

Answer 16

B antigen

Question 17

Antigens in group AB RBC

Answer 17

A & B antigens

Question 18

Antigens in group O RBC

Answer 18

None

Question 19

THE ABO blood group system is related to which chromosome

Answer 19

Chromosome 9

Question 20

THE Rh blood group system is related to which chromosome

Answer 20

Chromosome 1

Question 21

the presence of which antigen confers Rh to Rh +

Answer 21

the presence of D antigen

Question 22

the forward typing in pre-transfusion testing identifies

Answer 22

the ABO & Rh-D antigens

Question 23

the back typing in pre-transfusion testing identifies

Answer 23

Identifies corresponding iso-hemagglutinins in the serum

Question 24

importance of indirect coombs test

Answer 24

Screening of unexpected antibodies

Question 25

Identify the pre-transfusion test shown

Answer 25

cross- matching test

Question 26

what result of this test indicates incompatibility

Answer 26

Agglutination of the donor RBC

Question 27

transfusion threshold for packed RBc

Answer 27

7 g/dl

Question 28

Leukocytes induced adverse effects

Answer 28

febrile . non-haemolytic reactions

Question 29

plasma proteins , platelets . WBCs and micro aggregates can cause what reactions

Answer 29

Urticarial / febrile reactions

Question 30

to whom you must give washed RBCs

Answer 30

IgA deficient patients with anti IgA antibodies

Question 31

Viable T- lymphocytes can cause what disease

Answer 31

graft versus host disease

Question 32

Identify this immune reaction

Answer 32

Urticaria

Question 33

for invasive procedures / surgeries , what is the platelets target

Answer 33

50000

Question 34

Identify this procedure

Answer 34

Apheresis

Question 35

indications for fresh frozen plasma transfusion

Answer 35

DIC , liver disease , hereditary coagulation disorder , warfarin therapy reversal , massive transfusion

Question 36

granulocyte transfusion indications

Answer 36

febrile neutropenia with severe neutropenia

Question 37

Allergic transfusion reaction are mediated by

Answer 37

IgE mediated

Question 38

febrile , non-haemolytic transfusion reaction is due to

Answer 38

Cytokines released by Leukocytes

Question 39

acute haemolytic transfusion reaction is due to

Answer 39

IgM , mostly due to ABO incompatibility

Question 40

transfusion associated acute lung injury is manifested with

Answer 40

dyspnea , hypoxia & fever

Question 41

acute haemolytic transfusion reaction is manifested with

Answer 41

Urticaria , hypotension , fever . renal failure , lumbar pain