P3 PATHOLOGY Flashcards
Genetic predisposition for PAH
autosomal dominant
gene mutated in inherited PAH
bone morphogenetic protein (BMP) gene
lung diseases that can cause pulmonary hypertension
- COPD
- interstitial LUNG disease
- chronic hypoxia
Identify what is shown in the image
atherosclerosis& Atheromainthe large arteries
Identify what is shown in the image
Concentric non-laminar fibrosis & thickening of the intima
the arrow in the shown image is representing
Medial hypertrophy and broad collagen of adventitia
Identify what is shown in the image
Plexiform Lesion
Morphological changes in acute cor pulmonale
- RV shows only dilatation
- if sudden death happen, the heart size may even be normal
Morphological changes in the heart in chronic cor pulmonale
- RV markedly dilated with Thickening and hypertrophy of free wall of RV
Morphological changes in the lungs in chronic cor pulmonale
Pulmonary artery atheroma
& The underlying Lung pathology
the right arrow is indicating
Thickened interventricular septum
the left arrow is indicating
Thickened trabeculae
