P3 Chapter 19 BLOOD Flashcards
The presence of an abnormal hemoglobin molecule results in the inability of RBCs to maintain their shape when oxygen levels in the blood decrease. This condition is known as
a. hemophilia
b. leukemia
c. polycythemia
d. sickle-cell disease
d. sickle-cell disease
Which of the following would be a normal hematocrit in an adult male?
a. 22%
b. 36%
c. 47%
d. 73%
c. 47%
An inherited inability to produce clotting factor VIII or IX results in the condition known as
a. erythroblastosis fetalis
b. hemophilia
c. erythropenia
d. leukocytosis
b. hemophilia
Which blood cell type functions to phagocytize antigen-antibody complexes?
a. basophils
b. neutrophils
c. eosinophils
d. monocytes
c. eosinophils
The primary site of hemopoiesis in adult humans is in the
a. spleen
b. red bone marrow
c. liver
d. thymus
b. red bone marrow
Which of the following is an agranular leukocyte that leaves the blood and becomes a wandering macrophage?
a. monocyte
b. neutrophil
c. eosinophil
d. basophil
a. monocyte
Inadequate absorption of viatmin B12 leads to anemia.
a. hemorrhagic
b. pernicious
c. aplastic
d. hemolytic
b. pernicious
Which of the following is NOT a function of blood?
a. transport of dissolved gases
b. distribution of nutrients
c. restriction of fluid losses through damaged vessels
d. digestion of nutrients
d. digestion of nutrients
Which blood type in theory could be considered the “universal donor”?
a. A
b. B
c. O
d. AB
c. O
Plasma proteins which act as antibodies and attack foreign proteins are classified as
a. albumins
b. serotonin
c. gamma globulins
d. fibrin
c. gamma globulins
A chemical releaased by platelets that causes vasoconstriction after a blood vessel is damaged is
a. heparin
b. histamine
c. serotonin
d. erythropoietin
c. serotonin
The specific process by which red blood cells are formed is called
a. hemopoiesis
b. leukopoiesis
c. erythropoiesis
d. erythropoietin
c. erythropoiesis
When a blood vessel is damaged, clot formation includes the conversion of fibrinogen into _____ by the action of the enzyme _____
a. thrombin, prothrombin
b. thrombin, erythropoietin
c. fibrin, prothrombin
d. fibrin, thrombin
d. fibrin, thrombin
Chemotherapy tends to destroy normal marrow cells as well as cancerous cells. Which of the following might be used to stimulate hemopoiesis in a cancer patient?
a. histamine
b. albumins
c. intrinsic factor
d. erythropoietin
d. erythropoietin
The stem cell that differentiates to form all types of blood cells is the
a. myeloid stem cell
b. progranulocyte
c. proerythroblast
d. pluripotent stem cell
d. pluripotent stem cell
Which formed elements of the blood are produced from fragmentation of megakaryocytes?
a. lymphocytes
b. monocytes
c. thrombocytes
d. eosinophils
c. thrombocytes
Vascular spasms and platelet plug formation are steps in
a. hemostasis
b. homeostasis
c. agglutination
d. erythropoiesis
a. hemostasis
During clotting, prothrombin is activated to form
a. fibrin
b. fibrinogen
c. prothrombin activator
d. thrombin
d. thrombin
An individual who lacks A and B agglutinogens and has both A and B agglutinins has ABO blood type
a. A
b. B
c. O
d. AB
c. O
In the condition erythroblastosis fetalis (hemolytic disease of the newborn)
a. the mother’s blood cells hemolyze because the baby’s ABO antigens cross the placenta
b. the baby’s blood cells hemolyze because the mother’s ABO antibodies cross the placenta
c. the mother’s blood cells hemolyze because the baby’s Rh antigens cross the placenta
d. the baby’s blood cells hemolyze because anti-Rh antibodies produced by the mother cross the placenta
d. the baby’s blood cells hemolyze because anti-Rh antibodies produced by the mother cross the placenta
Which of the following blood diseases is characterized by the production of large numbers of immature leukocytes?
a. anemia
b. leukopenia
c. leukemia
d. polycythemia
c. leukemia
Which of the following begins the common pathway in clotting?
a. release of tissue factor,
b. formation of prothrombinase
c. formation of fibrinogen
d. release of thromboplastin
b. formation of prothrombinase
Fibrinolysis refers to
a. formation of an embolus
b. dissolution of a clot
c. rapid mitosis of fibroblasts at the edges of a damaged vessel
d. breakdown of fibrin to form fibrinogen
b. dissolution of a clot
An adult human contains about _____ of blood
a. 10 quarts
b. 2-3 pints
c. 4-6 liters
d. 2-3 gallons
c. 4-6 liters
Clotting may occur in an undamaged blood vessel. When that clot breaks loose and circulates through the bloodstream it is called
a. an aneurysm
b. an embolus
c. a thrombus
d. a thrombocyte
b. an embolus
Aged red blood cells are destroyed mainly by macrophages in the
a. lungs
b. kidneys
c. thymus
d. spleen
d. spleen
Which of the following statements is true?
a. Interleukin-7 stimulates the development of platelets
b. Red cells generate ATP anaerobically because they lack ribosomes
c. Biliverdin is produced from the breakdown of the non-iron portion of heme
d. A deficiency in the number of circulating red cells results in an increase in streptokinase activity
c. Biliverdin is produced from the breakdown of the non-iron portion of heme
Which of the following is true concerning the Rh blood group?
a. Presence or absence of Rh antigens is genetically determined
b. People with blood type B are really B negative
c. Being Rh- is associated with sickle-cell disease
d. Rh+ people can give blood to anyone
a. Presence or absence of Rh antigens is genetically determined
Blood makes up _____ of the total body weight
a. less than 10 percent
b. about half
c. 70 percent
d. almost all
a. less than 10 percen
The most abundant molecule present in blood plasma is
a. proteins called albumins
b. fibrinogen
c. glucose
d. water
d. water
A high reticulocyte count might indicate
a. low levels of hemoglobin in the red blood cells
b. increased production of red blood cells
c. the beginning of a disease
d. abnormal production of white blood cells
b. increased production of red blood cells
White blood cells are identified microscopically by the shape of their ______ and presence or absence of ______ in the cytoplasm
a. cell membrane, mitochondria
b. Golgi bodies, endoplasmic reticulum
c. nuclei, granules
d. mitochondria, hemoglobin
c. nuclei, granules
Neutrophils and macrophages are active in
a. phagocytosis
b. white blood cell formation
c. blood coagulation
d. antibody formation
a. phagocytosis
Which of the following is NOT a major function of the blood?
a) Transportation of nutrients
b) Regulation of blood pH
c) Protection against infectious disease
d) Transportation of heat
e) Production of oxygen
e) Production of oxygen
Which of the following is NOT a true statement regarding blood?
a) The normal average temperature of blood is around 100.4o F.
b) The normal pH range for blood is 7.35-7.45.
c) Hemocytoblasts are a common component of circulating blood.
d) The primary circulating blood cell is the RBC
e) Blood is a liquid connective tissue consisting of cells and a liquid extracellular matrix.
c) Hemocytoblasts are a common component of circulating blood.
The hematocrit is a measure of the percentage of whole blood occupied by
a) WBCs.
b) platelets.
c) RBCs.
d) plasma.
e) plasma proteins.
c) RBCs.
What percentage of blood plasma is water?
a) 95.1%
b) 91.5%
c) 88.5%
d) 4.9%
e) 8.5%
b) 91.5%
Which of the following plasma proteins plays a role in disease resistance?
a) Albumin
b) Globulins
c) Fibrinogen
d) Myoglobin
e) Hemoglobin
b) Globulins
Which of the following plasma proteins plays a role in blood clotting?
a) Albumin
b) Globulins
c) Fibrinogen
d) Prostaglandins
e) None of these choices
c) Fibrinogen
The process by which the formed elements of the blood develop is called
a) hematospermia.
b) hemopoiesis.
c) thrombocytosis.
d) hemostasis.
e) polycythemia.
b) hemopoiesis.
A megakaryoblast will develop into
a) a red blood cell.
b) a white blood cell.
c) a platelet.
d) either a white blood cell or a platelet.
e) none of these choices.
c) a platelet.
During hemopoiesis, some of the myeloid stem cells will eventually develop into
a) proerythroblasts.
b) T lymphoblasts.
c) B lymphoblasts.
d) NK lymphoblasts.
e) all of these choices.
a) proerythroblasts.
Which of the following hormones stimulates proliferation of red blood cells in red bone marrow?
a) erythropoietin (EPO)
b) thrombopoietin (TPO)
c) human growth hormone (hGH)
d) calcitonin (CT) e) follicle-stimulating hormone (FSH)
a) erythropoietin (EPO)
Approximately, how many hemoglobin molecules are found in each RBC?
a) 50 million
b) 100 million
c) 280 million
d) 320 million
e) 430 million
c) 280 million
Ferritin is a protein used to
a) transport iron in the blood.
b) store iron in the liver.
c) oxidize iron in the peroxisomes.
d) synthesize iron.
e) absorb iron across intestinal cells.
b) store iron in the liver.
The major function of red blood cells is
a) nutrient transport.
b) cytokine stimulation.
c) blood cell proliferation.
d) gas transport.
e) disease resistance.
d) gas transport.