other reproductive cancers Flashcards
1
Q
what is a germ cell tumour?
A
- 15-20% of all ovarian tumours
- Tertatoma
- Rarely becomes malignant – somatic malignancy e.g. SCC, thyroid ca
- Immature teratoma (embryonic tissues – rare)
2
Q
what is a mature germ cell tumour like?
A
Mature (benign, cystic) ‘dermoid cyst’ o 95% of germ cell tumours o Cystic, containing sebum and hair o Ectoderm, mesoderm and endoderm o Skin, respiratory epithelium, gut, fat common
3
Q
what are the other types of germ cell tumours which aren’t dermoid cysts?
A
Immature teratoma Dysgerminoma – most common malignant primitive germ cell tumour (1-2% of all malignant ovarian tumours) Yolk sac tumour Choriocarcinoma Mixed germ cell tumour
4
Q
what are the types of sex cord/stromal tumours?
A
fibroma/thecoma
granulosa cell tumour
sertoli-Leydig cell tumours
5
Q
what are the properties of a fibroma/thecoma?
A
benign
may produce oestrogen causing uterine bleeding
6
Q
what are the properties of a granulosa cell tumour?
A
all are potentially malignant
may be associated with oestrogenic manifestations
7
Q
what are the properties of Sertoli-Leydif cell tumours?
A
rare
may produce androgens
8
Q
how is vulval cancer managed?
A
wide local excision
+/- groin node dissection