Antenatal Screening Flashcards
Organisation of a low risk pregnancy?
All care = midwive delivered US appointment at 8-12 weeks Review: 16 weeks Anomaly scan: 20 weeks (US) Seen again: week 25,28,31,34,36 If no delivery seen at: week 38,40,41,42
Organisation of high risk pregnancy?
Care led by consultant obstetrician
Appointment schedule is determined case to case
8-12 week scan with midwife looks at?
Full history
Height, weight, BP
Blood tests
Types of blood tests at 8-12 week booking scan with midwife?
Hb ABO Rhesus status and AB Syphilis HIV Hep B and C
When is most accurate time to confirm viability, gestational age and delivery date estimate?
Secondary appointment for US
Crown rump length (CRL) does estimated delivery date and gestational age
What if estimated gestational age is not done at weeks 8-12?
It is then estimated using head circumference which is less accurate
What is used prior to US to predict EDD?
Naegele’s rule
- Based on onset of woman’s LMP add on 9 months 7 days to get due date
11 main conditions looked for in 20 week anomaly scan?
- Anencephaly
- Open spina bifida
- Cleft lip
- Diaphragmatic hernia
- Gastrochisis
- Exomphalos
- Serious cardiac abnormalities
- Bilateral renal agenesis
- Lethal skeletal dysplasia
- Edward’s syndrome
- Patau’s syndrome
What is T18?
Edward’s syndrome
What is T13?
Patau’s
Trisomy risk assessment in 1st trimester involves what?
Measuring nuchal translucency
Combined with HCG and PAPP-A blood test to given a risk level that the baby has down’s
What can be screening for in 2nd trimster?
Only T21 not T18/13
What is NIPT?
Non-invasive prenatal testing
-This detects fetal DNA fragments in a sample of blood taken from mother and is more accurate than combined test so can be offered to women identified as high risk from combined test (although can’t offer TOP based on this result as only screening test)
What is done as diagnostic testing for trisomy and when?
Amniocentesis after 15 weeks
Miscarriage rate <1%
Chorionic villus sampling after 12 weeks
Miscarriage rate <2%
What deficiencies scanned for at booking scan?
Iron anaemia
Folate
B12