Maternal Infections in Pregnancy Flashcards
Rubella risks?
Miscarriage if contracted in 1st semester and non-immune
Teratogenic
Rubella in early gestation consider what if ptnt isn’t immune
TOP
Risk of what syndrome in rubella?
Congenital rubella syndrome
- Cataract
- Cardiac abnormalities
- Deafness
What is Rubella?
Viral infection
Transmitted by direct contact/resp droplet exposure
Presnetation of rubella?
Fever
Rash
Lymphadenopathy
Polyarthritis
-Miscarriage, still birth, birth defects
-Birth defects: cataracts, cardiac issues, deafness
Management of Rubella?
- Rubella specific IgG Antibody can be detected after natural infection or vaccination
- Blood IgM should be done within 10 days of exposure
- If patient not immune consider TOP
- Supportive treatment: rest, fluids, paracetamol, avoid contact with other pregnant woman
What causes measles?
Paramyxovirus
Highly contagious
Presnetation of measles?
Fever White spots inside mouth Runny nose Cough Red eyed and rash Non teratogenic However fever can cause IUGR, microcephaly, miscarriage, stillbirth, preterm High mortality rate if mother develops pneumonia and encephalitis
Harm caused by measles?
Not teratogenic
- Bad fever can harm baby
What is chicken pox?
VZV is dna virus of herpes family
Transmission via droplets
Presnetation of chicken pox?
Fever Malaise Vesicular rash Primary infections Severe infection: he, encephalitis, pneumonia
Management of chiken pox?
Check for VSV immunity
Offer VZIG within 10 days of exposure
Ptt should avoid contact with other pregnants
Infective until lesions crust
Acyclovir considered if 20+ weeks (800mg x5 a day for 7 days)
Infection at 7-28 weeks?
Hypoplasia of limbs Psychomotor retardation IUGR Chorioretinal scarring Cataracts Microcephaly Cutaneous scarring
Risk of chicken pox before 28 weeks?
Fetal varicella syndrome and >28 weeks of neonatal VZV
What is CMV the leading cause of?
Deafness
