Ophthalmic Pharmaceuticals : Ocular Allergy Medications

Question 1

What is Histamine?

Answer 1

The stuff allergies are made of

Question 2

Where are chemical messengers stored?

Answer 2

Mast cells

Question 3

Where are neurotransmitters stored?

Answer 3

In the brain

Question 4

What does histamine do in our body?

Answer 4

Allergic reactions
Immune response
Gastric Acid Secretion
Neurotransmitter in brain

Question 5

What is the response if allergy antigens are detected?

Answer 5

Allergic response

Question 6

What is the response given to antigens?

IgG for an increase _____

Answer 6

Immune response

Question 7

What is Gastric Acid Secretion for?

Answer 7

Digestion

Question 8

What is limited in the brain?

Answer 8

Neurotransmitters

Question 9

What type of reaction can occur with histamines?

Answer 9

Anaphylaxis

Question 10

What are the types of Allergic Conjunctivitis?

Answer 10

• Seasonal
• Perennial
• Giant Papillary
• Vernal Kerato
• Atopic Kerato

Question 11

What type of allergic conjunctivitis associates with pollen, grass, spring?

Answer 11

Seasonal

Question 12

What type of allergic conjunctivitis associates with dander (pet), food?

Answer 12

Perennial

Question 13

What allergic reaction deposits onto contact lenses?

Answer 13

Giant Papillary

Question 14

What is the severe allergic reaction that occurs typically in spring and in young boys/teens?

Answer 14

Vernal

Question 15

What is the severe allergic reaction that involves the skin, people with eczema and is usually not so common?

Answer 15

Atopic

Question 16

What are Over the Counter Allergy Pharmaceuticals?

Answer 16

• Artificial Tears
• Vasoconstricors
• Mast Cell Stabilizers
• Anthistamines

Question 17

What are Prescribes Allergy Pharmaceuticals?

Answer 17

• Mast Cell Stabilizers
• Antihistamines
• Antihistamines with mast cell stabilizers
• Steroids
• NSAIDs

Question 18

What is the Mechanism of Action of a Mast Cell Stabilizer?

Answer 18

Prevent release of histamines from mast cells

Question 19

What are examples of Mast Cell Stabilizers?

Answer 19

Alomide (Lodoxamide Tromethamine Solution 0.1%)

Question 20

What are adverse effects of Mast Cell Stabilizers?

Answer 20

Burning
Stinging
Itching

Question 21

What is the Mechanism of Action of an Antihistamine/Mast Cell stabilizer?

Answer 21

Suppress migration of Eosinophils (Bepreve)

Question 22

What blocks histamine binding?

Answer 22

Antihistamine

Question 23

What block release of histamine?

Answer 23

Mast Cell Stabilizer

Question 24

What are examples of Antihistamine / Mast Cell Stabilizer?

Answer 24

Pataday (Olapotidine Hydrochloride Solution)
Zaditor (Ketotifen Fumarate Solution)
Bepreve (Bepotastine Besilate Solution)

Question 25

What is the Mechanism of Action of Corticosteroid?

Answer 25

Inhibits Phospholipase A2 Enzyme

Prevent release of Arachidonic Acid

Question 26

What enzyme is inhibited by Corticosteroids?

Answer 26

Phospholipase A2

Question 27

What does Corticosteroid prevent to release?

Answer 27

Arachidonic Acid

Question 28

What is an example of a Corticosteroid?

Answer 28

Alrex (Loteprenol Etabonate Suspension)

Question 29

What is the Mechanism of Action of NSAIDs?

Answer 29

Inhibit COX 1 and COX 2

Prevents prostaglandin production

Question 30

What enzymes do NSAID’s inhibit?

Answer 30

COX 1 and COX 2

Question 31

What does NSAID prevent to produce?

Answer 31

Prostaglandin

Question 32

What are examples of NSAID’s?

Answer 32

Acular LS (Ketoralac Tromethamine sol 0.4%)

Question 33

What are Adverse Effects of NSAID’s?

Answer 33

Burning, Stinging, Hyperemia
Corneal Ulceration
Corneal Melts