Ophthalmic Pharmaceuticals : Corticosteroids / Antibiotic Combo Flashcards
Corticosteroid combined with an antibiotic
Yes
What is the Ophthalmic Use?
Bacterial Conjunctivitis
What is Belphamide?
Sulphonamide Antibiotic with Corticosteroid
Blephamide ex.
Sodium Sulphacetamide 10%
Prednisolone Acetate 0.2%
What are adverse effects of Blephamide?
Allergic Reaction
Stevens Johnson Syndrome
Elevated IOP
Cataract Formation
Susp, Ung or Sol :
Blephamide
Susp or Ung
What is Tobradex?
Aminoglycoside Antibiotic with Corticosteroid
Tobradex ex.
Tobramycin 0.3%
Dexamethasone 0.1%
Susp, Ung or Sol :
Tobradex
All
What are adverse effects of Tobradex?
Allergic reactions
Elevated IOP
Cataracts
What is Maxitrol?
Aminoglycoside Antibiotics with Corticosteroid
Maxitrol ex.
Neomycin
Polymyxin B
Dexamethasone
Susp, Ung or Sol :
Maxitrol
Susp or Ung
What are adverse effects for Maxitrol?
Allergic reactiosn
Elevated IOP
Cataracts
What is Zylet?
Aminoglycoside and Corticosteroid
Zylet ex.
Tobramycin 0.3%
Loteprednol Etabonate 0.5%
What are adverse effects of Zylet?
Less risk of IOP elevation
Allergic reaction with tobramycin
Is Zylet available in Canada?
No
What ENHANCES immune system against tumours, infectious diseases, aids
Immunstimulators
What REDUCE immune response in organ transplant, allergies and inflammatory disorders?
Immunosuppressive
What are diseases or conditions that require ophthalmic immunodulators?
Corneal Transplants Sjogren's Syndrome Rheumatoid Arthritis Lupus Vernal and Atopic Keratoconjunctivitis
What is often on long terms corticosteroids but less risk of high pressure?
Corneal Transplants
What syndrome causes severely dry eyes and dry mouth, often associated with RA and lupus?
Sjogren’s Syndrome
What is an autoimmune disease where immune system attacks healthy cells, primarily attacks the joints, but can also be in the lungs, heart and eyes?
Rheumatoid Arthritis
What is an autoimmune disease where immune system attacks healthy cells, also attacks the joints, internal organs and skin having more life threatening complications?
Lupus
What keratoconjunctivitis is severe ocular allergy affects mainly children?
- young boy and teens
Vernal
What keratoconjunctivitis is severe ocular allergy affecting eyes and skin?
Atopic
What are the two keratoconjunctivitis?
Vernal and Atopic
What is the generic name for Restasis?
Cyclosporine Solution 0.05%
What is the Mechanism of Action of Restasis?
Inhibits inflammation in tear glands
Increase tear production
What is the Ophthalmic Use for Restasis?
Dry Eye disease
Sjogren’s Syndrome
What are adverse effects for Restasis
Conjunctival Hyperemia
Stinging, Epiphora, FB sensation
Blurry vision
What is the generic name Xiidra?
Lifitegrast solution 5%
What is the Mechanism of Action of Xiidra?
Competitively interferes with inflammatory cycle
What is the Ophthalmic Use for Xiidra?
Inflammatory dry eye disease
Sjogren’s Syndrome
What are adverse effects for Xiidra?
Metallic Aftertaste
Burning, stinging, irritation
Blurry vision