Ophthalmic Pharmaceuticals : Corticosteroids / Antibiotic Combo Flashcards

1
Q

Corticosteroid combined with an antibiotic

A

Yes

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2
Q

What is the Ophthalmic Use?

A

Bacterial Conjunctivitis

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3
Q

What is Belphamide?

A

Sulphonamide Antibiotic with Corticosteroid

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4
Q

Blephamide ex.

A

Sodium Sulphacetamide 10%

Prednisolone Acetate 0.2%

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5
Q

What are adverse effects of Blephamide?

A

Allergic Reaction
Stevens Johnson Syndrome
Elevated IOP
Cataract Formation

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6
Q

Susp, Ung or Sol :

Blephamide

A

Susp or Ung

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7
Q

What is Tobradex?

A

Aminoglycoside Antibiotic with Corticosteroid

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8
Q

Tobradex ex.

A

Tobramycin 0.3%

Dexamethasone 0.1%

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9
Q

Susp, Ung or Sol :

Tobradex

A

All

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10
Q

What are adverse effects of Tobradex?

A

Allergic reactions
Elevated IOP
Cataracts

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11
Q

What is Maxitrol?

A

Aminoglycoside Antibiotics with Corticosteroid

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12
Q

Maxitrol ex.

A

Neomycin
Polymyxin B
Dexamethasone

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13
Q

Susp, Ung or Sol :

Maxitrol

A

Susp or Ung

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14
Q

What are adverse effects for Maxitrol?

A

Allergic reactiosn
Elevated IOP
Cataracts

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15
Q

What is Zylet?

A

Aminoglycoside and Corticosteroid

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16
Q

Zylet ex.

A

Tobramycin 0.3%

Loteprednol Etabonate 0.5%

17
Q

What are adverse effects of Zylet?

A

Less risk of IOP elevation

Allergic reaction with tobramycin

18
Q

Is Zylet available in Canada?

A

No

19
Q

What ENHANCES immune system against tumours, infectious diseases, aids

A

Immunstimulators

20
Q

What REDUCE immune response in organ transplant, allergies and inflammatory disorders?

A

Immunosuppressive

21
Q

What are diseases or conditions that require ophthalmic immunodulators?

A
Corneal Transplants 
Sjogren's Syndrome 
Rheumatoid Arthritis 
Lupus 
Vernal and Atopic Keratoconjunctivitis
22
Q

What is often on long terms corticosteroids but less risk of high pressure?

A

Corneal Transplants

23
Q

What syndrome causes severely dry eyes and dry mouth, often associated with RA and lupus?

A

Sjogren’s Syndrome

24
Q

What is an autoimmune disease where immune system attacks healthy cells, primarily attacks the joints, but can also be in the lungs, heart and eyes?

A

Rheumatoid Arthritis

25
Q

What is an autoimmune disease where immune system attacks healthy cells, also attacks the joints, internal organs and skin having more life threatening complications?

A

Lupus

26
Q

What keratoconjunctivitis is severe ocular allergy affects mainly children?
- young boy and teens

A

Vernal

27
Q

What keratoconjunctivitis is severe ocular allergy affecting eyes and skin?

A

Atopic

28
Q

What are the two keratoconjunctivitis?

A

Vernal and Atopic

29
Q

What is the generic name for Restasis?

A

Cyclosporine Solution 0.05%

30
Q

What is the Mechanism of Action of Restasis?

A

Inhibits inflammation in tear glands

Increase tear production

31
Q

What is the Ophthalmic Use for Restasis?

A

Dry Eye disease

Sjogren’s Syndrome

32
Q

What are adverse effects for Restasis

A

Conjunctival Hyperemia
Stinging, Epiphora, FB sensation
Blurry vision

33
Q

What is the generic name Xiidra?

A

Lifitegrast solution 5%

34
Q

What is the Mechanism of Action of Xiidra?

A

Competitively interferes with inflammatory cycle

35
Q

What is the Ophthalmic Use for Xiidra?

A

Inflammatory dry eye disease

Sjogren’s Syndrome

36
Q

What are adverse effects for Xiidra?

A

Metallic Aftertaste
Burning, stinging, irritation
Blurry vision