Occular MOA Flashcards
Cyclosoporin/restasis
Dry eyes
T-cell inhibition
very dilute.05%
Visine
Red eyes
Class: occular astringent, anti redness
MOA: Vasoconstriction
Optivar
Conjunctivitis
Class: ocular antihistamine
MOA: HI blocker
Acular
Conjunctivitis: eye pain/swelling
Class: ocular NSAID
MOA: COX inhibition
NO increase for glaucoma or cataract like steroid
Polymyxin B/bacitracian
Bacterial conjunctivitis
Class: antibiotic
MOA: Protein synthesis inhibiton
Ara-A
Viral conjunctivitis
Antiviral for HSV
MOA: Inhibit viral DNA synthesis
Not for herpes zoster(shingles) doesn’t go deep enough
Timolol
Glaucoma
Reduce aqueas humor production by blocking epi
MOA: Beta blocker
caution systemic absorption and lung issues
Xalatan
Glaucoma
Increase draining of aqueous humor
MOA: Prostaglandin receptor agonist ON
turn iris brown, increase eyelash growth
Pilocarpine
Glaucoma
increase draining by tightening cilary muscles.
MOA: cholinergic agonist: parasympathetic,
side effects of all the drugs
local irritation
Prostaglanding receptor agonist ON
xalantan: glaucoma
T cell inhibition
Cyclosporin/restasis: dry eyes
COX receptor blocker
Acular: ocular NSAID conjunctivitis ; does not cause glaucoma or conjunctivitis
vasoconstriction
Visine: red eyes: rebound vasodilation
Cholonergic agonist
Pilocarpine: glaucoma, draining
