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pharmacology II > key convulsions > Flashcards

key convulsions Flashcards

1
Q

non specific anticonvulsant drugs

A

tegretol - neuronton

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2
Q

tegretol

A

reduce Na and CA across membraine - trigeminal nerualgia common first choice bone marrow supression

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3
Q

neuronton

A

Potientate gaba (mimic)- anticonvulsant and atypical analgesic - may decrease desire for meth - post herpetic neuralgia

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4
Q

partial seizures/focal

A

one part of brain- 60 percent

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5
Q

absence/

A

petit mal interupt conciousness - vacant 30 sec

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6
Q

tonic clonic

A

grand mal - jerking twitchin

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7
Q

status elipeticus

A

5 minutes or more medical emergency

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8
Q

drugs for focal

A

phenobarbital - myoline - dilantin

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9
Q

phenobarbitol

A

GAPA potientiation - long half life - children choice - low IQ - no alcohol

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10
Q

myoline

A

Barbituate GABA potientiation - Category D not for pregnancy in general - metabolite

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11
Q

dilantin

A

sodium channel block across membrane - Gum hyperplasia

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12
Q

Drugs for status epi

A

Dilantin - valium - atavan- zarontin

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13
Q

Valium

A

Benzo Gaba potientiation miller choice for SE

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14
Q

Atavan

A

ER drug of choice I think

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15
Q

zarontin

A

Calcium channel blockaide T - First choice for absence - Gums - lupus like syndrome

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16
Q

Dilantin

A

sodium channel block - GUMS - hepato toxic - bone marrow supression

17
Q

drugs for absence seizures

A

zarontin - klonopin

18
Q

klonopin

A

Benzo so GABA potientiation - abuse potential - tolerance - CNS depressant

19
Q

tonic clonic

A

Depakote - lamactil - topamox - keppra

20
Q

depakote

A

Enhance gaba transmission - GUMS hepatotoxic like dilantin - Birth defects - miller myoclonic choice

21
Q

Lamactil

A

Decrease glucamate sensitivity - anti excitatory - BIPOLAR - number one for grand mal

22
Q

keppra

A

Calcium movement blocker - pigment change

23
Q

what drug has a phenobarbitol as a metabolyte

A

myoline - so it has super long half life also. GABA potientiation all but absence

24
Q

what is dilantin not used for

A

ABSENCE seizures

25
Q

what is importaint to pay attention to with DILANTIN

A

lots of drug interactions

26
Q

what may help with giant gum side effect

A

CoQ10 and Folic acid supplementation

27
Q

what anticonvulsant should never be given with MAOIs

A

Tegretol - increase hypertensive crisis and aplastic anemia

28
Q

what seizure drug has additive effects when combines with other

A

Depakote -

29
Q

what drug causes serious side effects for fetus

30
Q

what drug must you worry about with neurontin

A

Antacids decreased absorption

pharmacology II (31 decks)

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