key anxiety and antidepressants Flashcards
What are the 7 anti depressants
Elavil - Trazodone - prozac - cymbalta - wellbutrin - zyban - deplin
in general, what is the purpose of the antidepressants
somehow increase the amount of serotonin-dopamine-and or NE in the cleft
Deplin
folic acid supplement - high dose 5-mthf - perscription only
zyban
NE and dopamine reuptake inhibitor - smokeing cessation
wellbutrin
NE and dopamine reuptake inhibitor - MAJOR Depression - ADD - nicotine receptor antagonist off
cymbalta
serotonin and NE reuptake inbibitor - Peripheral neuropathy - fibro - Major Depression
Prozac
SSRI - presyndaptic inhibiton - MAJOR Depress - Don’t mix with NSAID - bleed - GI - ED , wt gain, rebound depression - best bene/risk ratio
Trazodone
Tetracyclic - Serotonin inhib/partal antag off - INSOMNIA - Sedation - elderly fall risk
Elavil
Tricyclic - serotonin and NE - chronic pain, migrains - benedryl like sx
who are antidepressants moderately effective in
those with moderate to severe depression
what antidepressant class is most likely to induce serotonin syndrome
Monoamine oxidase inhibitors
Parq for MAOI
No tyramine foods - dried fruits, red wine - cheese and soy
what is serotonin syndrome
hypertensive emergencies and excelerated HTN
what would be the best antidepressant for severe depression and insomnia
Elavil - or trazodone the cyclic andi depressants
what is concerning about the cyclic antidepressantes
fatal at 10 tiems normal dose - arrythmias increased QT interval
side effects of the cyclics
benadryl like
number on choice for antidepresantes
prozac although there is side effect of anxiety, ED diarrhea and insomnia and weight gain
Black box warning cymbalta
suicide 18-24
why might someone pick wellbutrin
may cause weight loss insead of gain
what is deplin
neutraceutical adjunct - high dose methylated folic acid
pentothal
US - GABA - Cl - deadly withdrawl
pentobarbital
s - GAPA - CL - 15 min/6hr
fiorinal
I - GABA - Cl - 20-40/6/8
phenobarbital
L - GABA- CL 12 hrs - seizure - respiratory depression
versed
benzo - syrup for children endoscopy - retrograde amnesia
valium
benzo - Break through seizures-muscle relaxer
ambien
Benzo like - same effect Gaba - different receptor - Quick acting 15/3hrs - sleepwalking
lunesta
benzo like - insomnia 15min - no tolerance
deplin
melatonin agonist - MT1-2 - enhances action of melatoin
romazicon
Benzo antidote - benzo receptor antagonist - IV only
benzo overdose
tachycardia, seizures , high BP - intoxication signs CNS depression
barbituates mixed with alcohol
respiratory depression
when are barbs often used
pre-op
what may a functional GABA defect causes
possibly some epilesly
concerns with anxiolytics
tolerance - psychiological and physical dependency
