Obstetrics Flashcards
Describe the most common risk factor for uterine fibroids (leiomyomas)
Race, specifically Black race
Define primary dysmenorrhea
Lower crampy abdominal pain during menstruation in young females
How can endometriosis be diagnosed?
Laparoscopy is the investigation of choice
What is the first-line treatment for primary dysmenorrhea?
NSAIDs
Do young patients with adenomyosis benefit from oral contraceptive pills (OCP)?
Yes, they can be treated with OCPs
Describe the presentation of Mullerian agenesis
Normal female secondary development, no uterus, blind end vagina
What is the treatment for Androgen Insensitivity Syndrome after puberty?
Removal of testes
How is Turner syndrome characterized genetically?
45 XO karyotype
Describe the clinical features of Turner syndrome.
Short stature, low IQ, webbed neck, wide spaced nipples, congenital lymphedema, horseshoe kidney, cubitus valgus, and certain heart defects like coarctation of the aorta and bicuspid aortic valve.
What are the causes of hypothalamic pituitary failure?
Causes include anorexia, strenuous exercise, severe stress, and congenital conditions like Kallman syndrome.
Define Kallman syndrome and its clinical presentation.
Kallman syndrome is characterized by low GnRH, low FSH and LH levels, resulting in low estrogen and progesterone. It presents with anosmia and imperforate hymen.
How is imperforate hymen diagnosed and treated?
Diagnosed by cyclic abdominal pain, bulging bluish hymen on exam, and ultrasound showing a distended vagina and uterus. Treatment involves surgery under anesthesia.
Describe the clinical features and causes of secondary amenorrhea.
Clinical features include absence of menstruation, normal breasts, and a distended abdomen. Causes include obesity, excessive exercise, low body fat, anxiety, hyperprolactinemia, and other medical conditions.
What are the clinical features and investigations for polycystic ovarian syndrome (PCOS)?
Clinical features include irregular bleeding, obesity, acne, hirsutism, and infertility. Investigations show increased androgens, testosterone, LH, and a reversed LH: FSH ratio on blood tests, and a necklace appearance on ultrasound.
How is PCOS managed?
Management includes weight loss advice, OCPs for irregular bleeding and hirsutism, and clomiphene or gonadotropins for infertility. Metformin can be used for insulin resistance.
Describe the clinical features and treatment of congenital adrenal hyperplasia.
Features include salt-losing crisis in infancy, masculinized external genitalia in females, hirsutism, acne, and irregular cycles in adults. Treatment involves cortisone replacement.
Palpable gonads:
-Pelvic ultrasound
-Testosterone and dihydrotestosterone (DHT) ratio.
-LH and FSH.
-ACTH stimulation test.
-hCG stimulation test
No palpable gonads:
- markedly elevated 17-hydroxyprogesterone 90%
-Serum electrolytes.
-Plasma renin activity
What is the most common cause of idiopathic hirsutism and its treatment?
Idiopathic hirsutism is the most common cause of hirsutism without virilization. It is treated with spironolactone. Premature ovarian failure is characterized by menopausal symptoms before age 30 with a positive family history.
Describe the treatment approach for a patient with increased FSH who wants to have kids.
Hormone replacement therapy (HRT)
In Women:
Menopause:
During menopause, the ovaries reduce their production of estrogen and progesterone. In response, the pituitary gland releases more FSH to stimulate the ovaries, leading to high FSH levels.
Primary Ovarian Insufficiency (POI):
Also known as premature ovarian failure, POI is characterized by the loss of normal ovarian function before age 40. High FSH levels indicate the ovaries are not responding adequately to stimulation.
Polycystic Ovary Syndrome (PCOS):
Women with PCOS may have higher levels of FSH as part of the hormonal imbalances associated with the condition, though elevated LH (luteinizing hormone) is more common.
What is the recommended treatment for a patient with increased FSH who does not want to have kids and is sexually active?
Oral contraceptive pills (OCP)
How would you manage vaginal discharge in a female neonate with bloody discharge a few days after delivery?
Reassure
Define physiologic leucorrhea.
Clear or thin whitish discharge with no offensive odor or itching
What is the most common cause of bacterial vaginosis?
Gardnerella vaginalis
Describe the clinical presentation of bacterial vaginosis.
Thin, grayish-white discharge with a fishy odor
What is the drug of choice for treating bacterial vaginosis?
Metronidazole
How would you manage a patient with trichomonas vaginalis infection during pregnancy?
Metronidazole
Do you need to treat the partner of a patient with trichomonas vaginalis infection?
Yes, it is necessary
Define candida and list some risk factors for its occurrence.
A non-sexually transmitted infection; Risk factors include diabetes, immunodeficiency, prolonged antibiotic use, and pregnancy
What is the recommended treatment for candida infection with recurrent vulvovaginitis?
Oral fluconazole
How would you manage a cervical polyp presenting with bleeding after sexual intercourse?
Twisting
Finger liks projections
Describe the clinical presentation of cervicitis.
Mucopurulent cervical discharge
What are the most common causative organisms of cervicitis?
Chlamydia and gonorrhea