NALOXONE Flashcards
What is Naloxone?
Naloxone is an opioid receptor antagonist used for the management and reversal of opiate overdose.
What is the presentation of Naloxone?
Naloxone is presented in ampoules of 400 mcg/mL (0.4 mg in 1 mL) or Minijet syringe.
How is Naloxone administered?
Naloxone can be administered via IV, IM, SC, or IN.
What are the indications for Naloxone?
Indications include inadequate respiration and/or altered level of consciousness (ALoC) following known or suspected narcotic overdose.
What are the contraindications for Naloxone?
Contraindications include known severe adverse reactions.
What are the usual dosages for adults using Naloxone?
Adult dosages: 400 mcg IV/IO (AP) (repeat after 3 min PRN to a max dose of 2 mg), 400 mcg IM/SC (P) (repeat after 3 min PRN to a max dose of 2 mg), 800 mcg IN (EMT) (repeat x 1 after 3 min PRN).
What are the usual dosages for pediatric patients using Naloxone?
Pediatric dosages: 10 mcg/kg IV/IO (AP), 10 mcg/kg IM/SC (P), 20 mcg/kg IN (EMT). Repeat dose PRN to maintain opioid reversal to max 0.1 mg/kg or 2 mg.
What are the side effects of Naloxone?
Side effects include acute reversal of narcotic effects ranging from nausea and vomiting to agitation and seizures.
What additional information should be considered when administering Naloxone?
Use with caution in pregnancy and to patients who have taken large doses of narcotics or are physically dependent. Rapid reversal may precipitate acute withdrawal syndrome. Prepare to deal with aggressive patients.
